Izumi Horikawa, M.D., Ph.D.
Cancer and aging research, with special interest in telomeres, cellular senescence, microRNA and p53
Downregulation of splicing factor SRSF3 induces p53ß, an alternatively spliced isoform of p53 that promotes cellular senescence.Oncogene. 32: 2792-8, 2013. [ Journal Article ]
- J. Clin. Invest.. 123: 5247-57, 2013. [ Journal Article ]
Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease.PLoS ONE. 7: e44156, 2012. [ Journal Article ]
- Aging. 3: 26-32, 2011. [ Journal Article ]
- Nat. Cell Biol.. 12: 1205-1212, 2010. [ Journal Article ]
1995 Postdoctoral fellow, NIEHS, Research Triangle Park, NC 1999 Research fellow, NIEHS, Research Triangle Park, NC 2002 Staff Scientist, CCR, NCI, Bethesda, MD