Michael J. Kruhlak, Ph.D.
Dr. Kruhlak directs the activities of the CCR Confocal Microscopy Core that supports the light microscopy imaging needs of NCI researchers. This includes developing novel imaging-based assays based on high-resolution confocal, multi-photon, and super-resolution imaging methods.
1) confocal microscopy, 2) multi-photon imaging, 3) Airyscan super-resolution, 4) structured illumination microscopy, 5) live cell imaging, 6) lightsheet microscopy
Selected Key Publications
Generation of tumor antigen-specific iPSC-derived thymic emigrants using a 3D thymic culture system.Cell Reports. 22(12): 3175-3190, 2018. [ Journal Article ]
- Nature Medicine. 23(10): 1176-1190, 2017. [ Journal Article ]
- Cell Reports. 8(4): 1049-1062, 2014. [ Journal Article ]
- Nature. 447(7145): 730-734, 2007. [ Journal Article ]
- Journal of Cell Biology. 172(6): 823-834, 2006. [ Journal Article ]
Dr. Kruhlak received his Ph.D. from the Department of Biochemistry and Molecular Biology at the University of Calgary Medical School. From there, in 2001, he joined the NCI as a staff scientist to head the Experimental Immunology Branch Light Microscopy and Digital Imaging Facility. In 2018, as a NCI associate scientist he became director of the CCR Confocal Microscopy Core.
|Langston Lim||Research Biologist|