Zbigniew  Dauter, Ph.D.

Zbigniew Dauter, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Center for Structural Biology


Dr. Dauter headed the Synchrotron Radiation Research Section, which was located at the Argonne National Laboratory, the site of the largest U.S. synchrotron facility. He used X-ray diffraction techniques to solve crystal structures of various proteins and nucleic acids of biological and medical relevance. Dr. Dauter specialized in analyzing crystal structures at extremely high resolution and accuracy, in developing methods of effective diffraction data collection and in using weak anomalous dispersion effects to solve structures of macromolecules.

Areas of Expertise

Structural Biology
Macromolecular Crystallography
Diffraction Data Collection
Use Of Anomalous Diffraction For Phasing


Selected Key Publications

Molecular basis of agonism and antagonism in the oestrogen receptor

Brzozowski AM, Pike AC, Dauter Z, Hubbard RE, Bonn T, Engström O, Ohman L, Greene GL, Gustafsson JA, Carlquist M.
Nature. 389: 753-8, 1997. [ Journal Article ]

Triclinic lysozyme at 0.65 Å resolution

Wang J, Dauter M, Alkire R, Joachimiak A, Dauter Z.
Acta Crystallogr. D Biol. Crystallogr. 63: 1254-68, 2007. [ Journal Article ]

Human Suv3 protein reveals unique features among SF2 helicases

Jedrzejczak R, Wang J, Dauter M, Szczesny RJ, Stepien PP, Dauter Z.
Acta Crystallogr. D Biol. Crystallogr. 67: 988-96, 2011. [ Journal Article ]

High regularity of Z-DNA revealed by ultra high-resolution crystal structure at 0.55 Å

Brzezinski K, Brzuszkiewicz A, Dauter M, Kubicki M, Jaskolski M, Dauter Z.
Nucleic Acids Res. 39: 6238-48, 2011. [ Journal Article ]

Data collection for crystallographic structure determination

Rajashankar K, Dauter Z.
Methods Mol. Biol. 1140: 211-37, 2014. [ Journal Article ]