Yue Hu, Ph.D.

Yue Hu, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
  • Building 50, Room 1408
  • Bethesda, MD 20892-8010
  • 240-760-6372
Genetics Branch


Dr. Hu uses statistical and bioinformatics tools to investigate and integrate raw datasets of different types, to recognize statistically significant signals, and to identify the genes and pathways that potentially may be related to cancer development and metastasis.

Areas of Expertise

Statistical Analysis


Selected Recent Publications

Single-cell genetic analysis reveals insights into clonal development of prostate cancers and indicates loss of PTEN as a marker of poor prognosis

Heselmeyer-Haddad KM, Berroa Garcia LY, Bradley A, Hernandez L, Hu Y, Habermann JK, Dumke C, Thorns C, Perner S, Pestova E, Burke C, Chowdhury SA, Schwartz R, Schäffer AA, Paris PL, Ried T.
Am J Pathol. 184(10): 2671-86, 2014. [ Journal Article ]

LGR5 positivity defines stem-like cells in colorectal cancer

Hirsch D, Barker N, McNeil N, Hu Y, Camps J, McKinnon K, Clevers H, Ried T, Gaiser T.
Carcinogenesis. 35(4): 849-58, 2014. [ Journal Article ]

Aneuploidy, oncogene amplification and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells

Padilla-Nash HM, McNeil NE, Yi M, Nguyen QT, Hu Y, Wangsa D, Mack DL, Hummon AB, Case C, Cardin E, Stephens R, Difilippantonio MJ, Ried T.
Carcinogenesis. 34(8): 1929-39, 2013. [ Journal Article ]

Single-cell genetic analysis of ductal carcinoma in situ and invasive breast cancer reveals enormous tumor heterogeneity yet conserved genomic imbalances and gain of MYC during progression

Heselmeyer-Haddad K, Berroa Garcia LY, Bradley A, Ortiz-Melendez C, Lee WJ, Christensen R, Prindiville SA, Calzone KA, Soballe PW, Hu Y, Chowdhury SA, Schwartz R, Schäffer AA, Ried T.
Am J Pathol. 181(5): 1807-22, 2012. [ Journal Article ]

Molecular patterns in the evolution of serrated lesion of the colorectum

Gaiser T, Meinhardt S, Hirsch D, Killian JK, Gaedcke J, Jo P, Ponsa I, Miró R, Rüschoff J, Seitz G, Hu Y, Camps J, Ried T.
Int J Cancer. 132(8): 1800-10, 2013. [ Journal Article ]