William C. Reinhold, B.S.

William C. Reinhold, B.S.

  • Center for Cancer Research
  • National Cancer Institute
Developmental Therapeutics Branch


William Reinhold runs the CellMiner website , generates data for inclusion in it, organizes that data in an intuitive fashion, develops the software to facilitate the use of that data, and accesses that data scientifically. CellMiner includes data for the NCI-60 cancerous cell lines, and is a premier systems pharmacology resource, including data from 18 platforms. We provide the unmatched Developmental Therapeutics Program  activity data for 20,002 compounds (including 114 FDA-approved drugs, and 55 in clinical trial). Multiple forms of molecular data is provided. The user may select any of these input parameters of interest (e.g., a gene, drug, microRNA) for cross comparison.

Areas of Expertise

Molecular Data


Selected Publications

CellMiner: a web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set

Reinhold WC, Sunshine M, Liu H, Varma S, Kohn KW, Morris J, Doroshow J, Pommier Y.
Cancer Res.. 72: 3499-511, 2012. [ Journal Article ]

Multifactorial regulation of E-cadherin expression: an integrative study

Reinhold WC, Reimers MA, Lorenzi P, Ho J, Shankavaram UT, Ziegler MS, Bussey KJ, Nishizuka S, Ikediobi O, Pommier YG, Weinstein JN.
Mol. Cancer Ther.. 9: 41655, 2010. [ Journal Article ]

Exon array analyses across the NCI-60 reveal potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intron

Reinhold WC, Mergny JL, Liu H, Ryan M, Pfister TD, Kinders R, Parchment R, Doroshow J, Weinstein JN, Pommier Y.
Cancer Res.. 70: 2191-203, 2010. [ Journal Article ]

Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents

Zoppoli G, Regairaz M, Leo E, Reinhold WC, Varma S, Ballestrero A, Doroshow JH, Pommier Y.
Proc. Natl. Acad. Sci. U.S.A.. 109: 15030-5, 2012. [ Journal Article ]

The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology

Abaan OD, Polley EC, Davis SR, Zhu YJ, Bilke S, Walker RL, Pineda M, Gindin Y, Jiang Y, Reinhold WC, Holbeck SL, Simon RM, Doroshow JH, Pommier Y, Meltzer PS.
Cancer Res.. 73: 4372-82, 2013. [ Journal Article ]


Bioinformatics Specialist (Contr.)
Fathi Elloumi, Ph.D.
Bioinformatics Specialist (Contr.)
Sudhir Varma, Ph.D.
Bioinformatics Specialist (Contr.)
Yanghsin (Jeffrey) Wang