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Uma T. Shankavaram, Ph.D.

Uma T. Shankavaram, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Radiation Oncology Branch

RESEARCH SUMMARY

Dr. Shankavaram manages the Radiation Oncology Branch’s Microarray Core Facility (MCF), which provides services and access to new technologies to investigators from NCI and other NIH institutes. The MCF offers special expertise in gene expression array hybridization, statistical analysis, genetics/genomics, and technical support.

  • Gene Expression Arrays:   gene chip processing of cDNA and Affymetrix arrays
  • Boinformatics Analysis:  consultation with scientists prior to experiments, analysis of high-throughput sequencing, gene expression, metabolomics, proteomics and other biological data, including functional and gene set enrichment analysis
  • Application Development:  develops custom applications to enhance research through web applications for data analysis, databases, visualization, and custom analysis tools
  • Training:  informal training to assist researchers in using computational tools

Areas of Expertise

bioinformatics, genetics, genomics, high-throughput data analysis, statistical and computational methods, web application development

Publications

Selected Publications

Chemoirradiation for glioblastoma multiforme: the national cancer institute experience

Ho J, Ondos J, Ning H, Smith S, Kreisl T, Iwamoto F, Sul J, Kim L, McNeil K, Krauze A, Shankavaram U, Fine HA, Camphausen K.
PLoS ONE. 8: e70745, 2013. [ Journal Article ]

Genotype and tumor locus determine expression profile of pseudohypoxic pheochromocytomas and paragangliomas

Shankavaram U, Fliedner SM, Elkahloun AG, Barb JJ, Munson PJ, Huynh TT, Matro JC, Turkova H, Linehan WM, Timmers HJ, Tischler AS, Powers JF, de Krijger R, Baysal BE, Takacova M, Pastorekova S, Gius D, Lehnert H, Camphausen K, Pacak K.
Neoplasia. 15: 435-47, 2013. [ Journal Article ]

StRAP: An Integrated Resource for Profiling High-Throughput Cancer Genomic Data from Stress Response Studies

Johnson S, Issac B, Zhao S, Bisht M, Celiku O, Tofilon P, Camphausen K, Shankavaram U.
PLoS ONE. 7: e51693, 2012. [ Journal Article ]

CD44 is prognostic for overall survival in the NCI randomized trial on breast conservation with 25 year follow-up

Dan T, Hewitt SM, Ohri N, Ly D, Soule BP, Smith SL, Matsuda K, Council C, Shankavaram U, Lippman ME, Mitchell JB, Camphausen K, Simone NL.
Breast Cancer Res. Treat.. 143: 41951, 2014. [ Journal Article ]

The ATP-competitive mTOR inhibitor INK128 enhances in vitro and in vivo radiosensitivity of pancreatic carcinoma cells

Hayman TJ, Wahba A, Rath BH, Bae H, Kramp T, Shankavaram UT, Camphausen K, Tofilon PJ.
Clin. Cancer Res.. 20: 110-9, 2014. [ Journal Article ]

Team

Research Fellow
Shaoli Das, Ph.D.
Programmer Analyst III (Contr.)
Xiang Deng