Tito Mendoza

Tito R. Mendoza, Ph.D., M.S., M.Ed.

  • Center for Cancer Research
  • National Cancer Institute
Office of Patient-Centered Outcomes Research


Tito Mendoza is a psychometrician who was instrumental in the development and validation of several multi-symptom and single symptom assessment tools. He was involved in several aspects of the development and validation of the patient-reported outcomes version of the Common Terminology Criteria Adverse Event (PRO-CTCAE) funded by the National Cancer Institute. His collaborative interests are in the design, analysis and interpretation of studies incorporating patient-reported outcomes (PRO) in early phase clinical trials.

Areas of Expertise

1) psychometrics 2) validation 3) symptom assessment 4) patient-reported outcomes 5) statistics 6) measurement


Selected Key Publications

Patient-reported symptom burden in patients with rare cancers receiving pembrolizumab in a phase II Clinical Trial

Mendoza TR, Hong DS, Peterson CB, Stephen B, Dumbrava E, Pant S, Tsimberidou AM, Yap TA, Sheshadri A, Altan M, George G, Castillo L, Rodriguez E, Gong J, Subbiah V, Janku F, Fu S, Piha-Paul SA, Ahnert JR, Karp DD, Cleeland C, Meric-Bernstam F, Naing A.
Sci Rep. 12(1): 14367, 2022.
Full-Text Article
[ Journal Article ]

Evaluating the psychometric properties of the Immunotherapy module of the MD Anderson Symptom Inventory

Mendoza T, Sheshadri A, Altan M, Hess K, George G, Stephen B, Castillo L, Rodriguez E, Gong J, Peterson C, Rodon Ahnert J, Fu S, Piha-Paul SA, Pant S,
Dumbrava E, Yap TA, Janku F, Tsimberidou AM, Subbiah V, Karp DD, Zarifa A, McQuinn LM, Cleeland C, Hong DS, Naing A.
J Immunother Cancer. 8(2): e000931, 2020.
Full-Text Article
[ Journal Article ]

The Treatment-induced Neuropathy Assessment Scale (TNAS): a psychometric update following qualitative enrichment

Mendoza TR, Williams LA, Shi Q, Wang XS, Bamidele O, Woodruff JF, Cleeland CS.
J Patient Rep Outcomes. 4(1): 15, 2020.
Full-Text Article
[ Journal Article ]

Evaluation of different recall periods for the US National Cancer Institute's PRO-CTCAE

Mendoza TR, Dueck AC, Bennett AV, Mitchell SA, Reeve BB, Atkinson TM, Li Y, Castro KM, Denicoff A, Rogak LJ, Piekarz RL, Cleeland CS, Sloan JA, Schrag D, Basch E.
Clin Trials. 14(3): 255-263, 2017.
Full-Text Article
[ Journal Article ]

The rapid assessment of fatigue severity in cancer patients: use of the Brief Fatigue Inventory

Mendoza TR, Wang XS, Cleeland CS, Morrissey M, Johnson BA, Wendt JK, Huber SL.
Cancer. 85(5): 1186-96, 1999. [ Journal Article ]