Sweta Sikder, Ph.D.
- Center for Cancer Research
- National Cancer Institute
- Building 41, Room B1300
- Bethesda, MD 20892
- 240-760-7449
- sweta.sikder@nih.gov
RESEARCH SUMMARY
The dynamic nucleoprotein complex chromatin dictates various physiological functions of the cell. There is a gradual but significant change in the structure and integrity of the chromatin as the cells age resulting in a modified epigenetic landscape and thereby altered gene expression. Sweta is interested in deciphering the roles of histone variants in regulating chromatin structure during cellular senescence and in cancer.
Areas of Expertise
Chromatin Organization
Epigenetics
Senescence
Cancer