Stephen M. Hewitt, M.D., Ph.D.

Stephen M. Hewitt, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Laboratory of Pathology


The Experimental Pathology Laboratory (EPL) is focused on translational pathology research. The EPL focuses on collaborative research projects within the Laboratory of Pathology, as well as provides core laboratory support. Areas of expertise within the EPL include: histology, immunohistochemistry, tissue microarray construction and application, micro-dissection technologies, in situ assays for RNA and DNA, whole slide imaging, image analysis and tissue proteomics.

Areas of Expertise

Translational Pathology
Tissue Microarrays
Pre-analytic Variables Of Tissue
Whole Slide Imaging


Selected Publications

Profiling of Phospho-AKT, Phospho-mTOR, Phospho-MAPK and EGFR in Non-small Cell Lung Cancer

Kitano H, Chung JY, Ylaya K, Conway C, Takikita M, Fukuoka J, Doki Y, Hanaoka J, Hewitt SM.
J. Histochem. Cytochem.. 2014. [ Journal Article ]

Application of Selected Reaction Monitoring for Multiplex Quantification of Clinically Validated Biomarkers in Formalin-Fixed, Paraffin-Embedded Tumor Tissue

Hembrough T, Thyparambil S, Liao WL, Darfler MM, Abdo J, Bengali KM, Hewitt SM, Bender RA, Krizman DB, Burrows J.
J Mol Diagn. 2013. [ Journal Article ]

Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression

Horne HN, Sherman ME, Garcia-Closas M, Pharoah PD, Blows FM, Yang XR, Hewitt SM, Conway CM, Lissowska J, Brinton LA, Prokunina-Olsson L, Dawson SJ, Caldas C, Easton DF, Chanock SJ, Figueroa JD.
Breast Cancer Res. Treat.. 2013. [ Journal Article ]

Expression of stress-induced phosphoprotein1 (STIP1) is associated with tumor progression and poor prognosis in epithelial ovarian cancer

Cho H, Kim S, Shin HY, Chung EJ, Kitano H, Hyon Park J, Park L, Chung JY, Hewitt SM, Kim JH.
Genes Chromosomes Cancer. 53: 277-88, 2014. [ Journal Article ]

Multiplex Quantitative Measurement of mRNAs From Fixed Tissue Microarray Sections

Armani M, Tangrea M, Yang B, Rosenberg A, Ylaya K, Morris J, Rodriguez-Canales J, Hanson J, Shapiro B, Emmert-Buck MR, Smela E, Hewitt SM.
Diagn. Mol. Pathol.. 2014. [ Journal Article ]


Biochemist (Contr.)
Hye-Jung Chung, Ph.D.
Joon Yong Chung, Ph.D.
Biomedical Engineer
Jeffrey Hanson, M.S.
Candice Perry
Histopathology Technician
Kris Ylaya