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Stacey Doran, M.D.

Stacey Doran, M.D.

  • Center for Cancer Research
  • National Cancer Institute
Center for Immuno-Oncology

RESEARCH SUMMARY

Dr. Doran is a medical oncologist with an interest in adoptive cellular therapies. She collaborates with other researchers within the Center for Immuno-Oncology (CIO) to create new treatments using immune cells for patients with a wide variety of cancers including human-papillomavirus (HPV)-associated malignancies (e.g. cervical, anal, and head & neck cancers), breast cancer, and other solid tumors. Dr. Doran treats patients on early-phase clinical trials using new immunotherapies.

Areas of Expertise

Cellular Therapy
Immunotherapy
Clinical Trials
Solid Tumors
Human Papillomavirus (HIV)
Health Disparities

Publications

Selected Key Publications

T-Cell Receptor Gene Therapy for Human Papillomavirus-Associated Epithelial Cancers: A First-in-Human, Phase I/II Study

Stacey L Doran 1, Sanja Stevanović 1, Sabina Adhikary 2, Jared J Gartner 1, Li Jia 1, Mei Li M Kwong 1, William C Faquin 3, Stephen M Hewitt 1, Richard M Sherry 1, James C Yang 1, Steven A Rosenberg 1, Christian S Hinrichs 1
Journal of Clinical Oncology. 18.02424: 2759-2768, 2019.
Full-Text Article
[ Journal Article ]

TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers

Nisha B Nagarsheth 1, Scott M Norberg 1, Andrew L Sinkoe 1, Sabina Adhikary 2, Thomas J Meyer 3 4, Justin B Lack 4 5, Andrew C Warner 6, Colleen Schweitzer 2, Stacey L Doran 7, Soumya Korrapati 1, Sanja Stevanović 7, Cornelia L Trimble 8, Jennifer A Kanakry 7, Mohammad Hadi Bagheri 9, Erin Ferraro 10, Stephanie H Astrow 2, Adrian Bot 2, William C Faquin 11, David Stroncek 12, Nikolaos Gkitsas 7, Steven Highfill 12, Christian S Hinrichs 13
Nature Medicine. 10.1038/s41591-020-01225-1: 419-425, 2021.
Full-Text Article
[ Journal Article ]

A Phase II Study of Tumor-infiltrating Lymphocyte Therapy for Human Papillomavirus-associated Epithelial Cancers

Sanja Stevanović 1, Sarah R Helman 1, John R Wunderlich 2, Michelle M Langhan 2, Stacey L Doran 1, Mei Li M Kwong 2, Robert P T Somerville 2, Christopher A Klebanoff 2, Udai S Kammula 2, Richard M Sherry 2, James C Yang 2, Steven A Rosenberg 2, Christian S Hinrichs 3
Clinical Cancer Research. 10.1158/1078-0432.CCR-18-2722: 1486-1493, 2019.
Full-Text Article
[ Journal Article ]

Hypertension, smoking, and preexistence of multiple cardiac risk factors correlate with carfilzomib-induced cardiovascular adverse events in a racially diverse population

Stacey Doran 1, Manu Mysore 2, Seyed Ebrahim Kassaian 3, Ethan Kotloff 2, Farin Kamangar 4, Ashkan Emadi 5 6 7, Jummai Apata 8, Brian Barr 2
Frontier Cardiovascular Medicine. 10:1129943: 2023.
Full-Text Article
[ Journal Article ]

Human Papillomavirus T-Cell Cross-reactivity in Cervical Cancer: Implications for Immunotherapy Clinical Trial Design

Sarah R Helman 1, Sanja Stevanovic 1, Tracy E Campbell 2, Mei Li M Kwong 3, Stacey L Doran 1, William C Faquin 4, Christian S Hinrichs 1
JAMA Open Network. 1(3):e180706: 2018.
Full-Text Article
[ Journal Article ]