Songjoon Baek, Ph.D.

Songjoon Baek, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute


Dr. Baek’s primary research interest is in computational biology and biostatistics.  He has made a significant impact on bioinformatics and biological interpretation of research involving analysis of DnaseI hypersensitive sites, digital genomic footprinting, and comparative enrichment analysis.  His contributions have led to a better understanding of the global chromatin landscape and the elucidation of transcriptional mechanisms.  Dr. Baek is also interested in the development of a novel bioinformatics algorithm for the analysis of high-throughput multi-omics data. 

Areas of Expertise

Computational Biology
DnaseI-seq Analysis
RNA-seq Analysis
Genomic Classification Algorithms
Gene Expression Analysis


Selected Publications

DNase Footprint Signatures Are Dictated by Factor Dynamics and DNA Sequence

Sung MH*, Guertin MJ*, Baek S*, and Hager GL. (*Co-first author)
Mol Cell. 56(2): 275-85, 2014. [ Journal Article ]

Molecular Architecture of Transcription Factor Hotspots in Early Adipogenesis

Siersbaek R, Baek S, Rabiee A, Nielsen R, Traynor S, Clark N, Sandelin A, Jensen ON, Sung MH, Hager GL, and Mandrup S.
Cell Rep. 7(5): 1434-42, 2014. [ Journal Article ]

Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions

Morris SA, Baek S, Sung MH, John S, Wiench M, Johnson TA, Schiltz RL, and Hager GL.
Nat Struct Mol Biol. 21(1): 73-81, 2013. [ Journal Article ]

Quantitative analysis of genome-wide chromatin remodeling

Baek S, Sung MH, and Hager GL.
Methods Mol Biol. 833: 433-41, 2012. [ Journal Article ]

Development of Biomarker Classifiers from High-Dimensional Data

Baek S, Tsai CA, and Chen JJ.
Brief Bioinform. 10(5): 537-46, 2009. [ Journal Article ]