National Cancer Institute - Cancer.gov

Scott Wilkinson

Scott Wilkinson, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Prostate Cancer Genetics Section

RESEARCH SUMMARY

Dr. Wilkinson is a cancer biologist with an interest in applying novel imaging approaches to molecular and cell biology. His current research explores cell-autonomous mechanisms of resistance to androgen deprivation therapy in locally advanced prostate cancer.

Areas of Expertise

1) Confocal microscopy, 2) multiplex immunofluorescence, 3) epithelial-to-mesenchymal transition

Publications

Selected Key Publications

Nascent Prostate Cancer Heterogeneity Drives Evolution and Resistance to Intense Hormonal Therapy

Scott Wilkinson, Huihui Ye, Fatima Karzai, Stephanie A. Harmon, Nicholas T. Terrigino, David J. VanderWeele, John R. Bright, Rayann Atway, Shana Y. Trostel, Nicole V. Carrabba, Nichelle C. Whitlock, Stephanie M. Walker, Rosina T. Lis, Houssein Abdul Sater, Brian J. Capaldo, Ravi A. Madan, James L. Gulley, Guinevere Chun, Maria J. Merino, Peter A. Pinto, Daniela C. Salles, Harsimar B. Kaur, Tamara L. Lotan, David J. Venzon, Peter L. Choyke, Baris Turkbey, William L. Dahut, Adam G. Sowalsky
European Urology. 2021.
Full-Text Article
[ Journal Article ]

A case report of multiple primary prostate tumors with differential drug sensitivity

Scott Wilkinson, Stephanie A. Harmon, Nicholas T. Terrigino, Fatima Karzai, Peter A. Pinto, Ravi A. Madan, David J. VanderWeele, Ross Lake, Rayann Atway, John R. Bright, Nicole V. Carrabba, Shana Y. Trostel, Rosina T. Lis, Guinevere Chun, James L. Gulley, Maria J. Merino, Peter L. Choyke, Huihui Ye, William L. Dahut, Baris Turkbey, Adam G. Sowalsky
Nature Communications. 2020.
Full-Text Article
[ Journal Article ]

An intra-tumoral niche maintains and differentiates stem-like CD8 T cells

Caroline S. Jansen, Nataliya Prokhnevska, Viraj A. Master, Martin G. Sanda, Jennifer W. Carlisle, Mehmet Asim Bilen, Maria Cardenas, Scott Wilkinson, Ross Lake, Adam G. Sowalsky, Rajesh M. Valanparambil, William H. Hudson, Donald McGuire, Kevin Melnick, Amir I. Khan, Kyu Kim, Yun Min Chang, Alice Kim, Christopher P. Filson, Mehrdad Alemozaffar, Adeboye O. Osunkoya, Patrick Mullane, Carla Ellis, Rama Akondy, Se Jin Im, Alice O. Kamphorst, Adriana Reyes, Yuan Liu, Haydn Kissick
Nature. 2019.
Full-Text Article
[ Journal Article ]

Sequential Prostate Magnetic Resonance Imaging in Newly Diagnosed High-risk Prostate Cancer Treated with Neoadjuvant Enzalutamide is Predictive of Therapeutic Response

Fatima Karzai, Stephanie M. Walker, Scott Wilkinson, Ravi A. Madan, Joanna H. Shih, Maria J. Merino, Stephanie A. Harmon, David J. VanderWeele, Lisa M. Cordes, Nicole V. Carrabba, John R. Bright, Nicolas T. Terrigino, Guinevere Chun, Marijo Bilusic, Anna Couvillon, Amy Hankin, Monique N. Williams, Rosina T. Lis, Huihui Ye, Peter L. Choyke, James L. Gulley, Adam G. Sowalsky, Baris Turkbey, Peter A. Pinto, William L. Dahut
Clinical Cancer Research. 2021.
Full-Text Article
[ Journal Article ]

Prostate-Specific Membrane Antigen Is a Biomarker for Residual Disease following Neoadjuvant Intense Androgen Deprivation Therapy in Prostate Cancer

John R. Bright, Rosina T. Lis, Anson T. Ku, Nicholas T. Terrigino, Nichelle C. Whitlock, Shana Y. Trostel, Nicole V. Carrabba, Stephanie A. Harmon, Baris Turkbey, Scott Wilkinson, Adam G. Sowalsky
Journal of Urology. 2022.
Full-Text Article

Team

Daniel Low
Postbaccalaureate Fellow (CRTA)
Daniel Low