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Rupali Sharma, Ph.D.

Rupali Sharma, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Surgical Oncology Program

RESEARCH SUMMARY

During her Ph.D. studies, Dr. Sharma worked with diabetic retinopathy (DR) patients to analyze telomere length as a prognostic marker of this disease. Along with this research, she also focused on the role of resveratrol on the expression of various candidate genes involved in DR in experimental models of diabetes induced in estrogen-deficient rats and controls. With her molecular biology and neuroscience background, Dr. Sharma has joined Dr Sadowski and her team in the hope of identifying novel prognostic markers and more effective therapies for neuroendocrine tumors. This research could potentially lead to better diagnosis and treatments for patients.

Areas of Expertise

1) In vivo rat and mouse model, 2) ELISA, 3) clinical research, 4) real-time polymerase chain reaction (qPCR), 5) cell culture, 6) Western blotting

Publications

Selected Key Publications

Chronic Exposure to High Altitude: Synaptic, Astroglial and Memory Changes

Sharma R, Cramer NP, Perry B, Adahman Z, Murphy EK, Xu X, Dardzinski BJ, Galdzicki Z, Perl DP, Dickstein DL, Iacono D.
Sci Rep. 9(1): 16406, 2019. [ Journal Article ]

Resveratrol regulates body weight in healthy and ovariectomized rats

Sharma R, Sharma NK, Thungapathra M.
Nutr Metab (Lond). 14: 30, 2017. [ Journal Article ]

Telomere mean length in patients with diabetic retinopathy

Sharma R, Gupta A, Thungapathra M, Bansal R.
Sci Rep. 5: 18368, 2015. [ Journal Article ]

Role of Ionizing Radiation in Neurodegenerative Diseases

Sharma NK, Sharma R, Mathur D, Sharad S, Minhas G, Bhatia K, Anand A, Ghosh SP.
Front Aging Neurosci. 10: 134, 2018. [ Journal Article ]