National Cancer Institute - Cancer.gov

R. Louis Schiltz headshot

R. Louis Schiltz, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Research Biologist
Laboratory of Receptor Biology and Gene Expression

RESEARCH SUMMARY

R. Louis Schiltz is a well published biochemist who studies the structure and function of nuclear receptors in transcriptional activation and repression. He utilizes his skills in biochemistry, molecular biology, cell biology, and bioinformatics to further the understanding of nuclear receptor function.

Areas of Expertise

Biochemistry
Molecular Biology
Cell Biology
Cell Culture
CRISPR

Publications

Selected Key Publications

Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism

Voss TC, Schiltz RL, Sung MH, Yen PM, Stamatoyannopoulos JA, Biddie SC, Johnson TA, Miranda TB, John S, Hager GL
Cell. 146(4): 544-554, 2011.
Full-Text Article
[ Journal Article ]

The transcriptional coactivators p300 and CBP are histone acetyltransferases

Ogryzko VV, Schiltz RL, Russanova V, Howard BH, Nakatani Y
Cell. 87(5): 953-959, 1996.
Full-Text Article
[ Journal Article ]

Histone-like TAFs within the PCAF histone acetylase complex

Ogryzko VV, Kotani T, Zhang X, Schiltz RL, Howard T, Yang XJ, Howard BH, Qin J, Nakatani Y
Cell. 94(1): 35-44, 1998.
Full-Text Article
[ Journal Article ]

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM
Cell. 90(3): 569-580, 1997.
Full-Text Article
[ Journal Article ]

Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions

Morris SA, Baek S, Sung MH, John S, Wiench M, Johnson TA, Schiltz RL, Hager GL
Nat Struct Mol Biol. 21(1): 73-81, 2014.
Full-Text Article
[ Journal Article ]