Prachi Mishra, Ph.D.

Prachi Mishra, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Surgical Oncology Program


Dr. Mishra is involved in clinical and preclinical research of endocrine cancers, including adrenocortical carcinoma and thyroid cancer. She specializes in cell biology, molecular biology, metabolomics and translational studies. She also has made important contributions in breast and prostate cancer metabolism studies.

Areas of Expertise

1) cell biology, 2) metabolomics, 3) translational sciences


Selected Key Publications

MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis

Terunuma A, Putluri N, Mishra P, Mathé EA, Dorsey TH, Yi M, Wallace TA, Issaq HJ, Zhou M, Killian JK, Stevenson HS, Karoly ED, Chan K, Samanta S, Prieto D, Hsu TY, Kurley SJ, Putluri V, Sonavane R, Edelman DC, Wulff J, Starks AM, Yang Y, Kittles RA, Yfantis HG, Lee DH, Ioffe OB, Schiff R, Stephens RM, Meltzer PS, Veenstra TD, Westbrook TF, Sreekumar A, Ambs S.
J Clin Invest. 124(1): 398-412, 2014. [ Journal Article ]

Metabolic Signatures of Human Breast Cancer

Mishra P, Ambs S.
Mol Cell Oncol. 2(3): e992217, 2015. [ Journal Article ]

ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming

Mishra P, Tang W, Putluri V, Dorsey TH, Jin F, Wang F, Zhu D, Amable L, Deng T, Zhang S, Killian JK, Wang Y, Minas TZ, Yfantis HG, Lee DH, Sreekumar A, Bustin M, Liu W, Putluri N, Ambs S.
J Clin Invest. 128(1): 323-340, 2017. [ Journal Article ]

ADHFE1 is a MYC-linked oncogene that induces metabolic reprogramming and cellular de-differentiation in breast cancer

Mishra P, Tang W, Ambs S.
Mol Cell Oncol. 5(3): e1432260, 2018. [ Journal Article ]

Multi-omic serum biomarkers for prognosis of disease progression in prostate cancer

Kiebish MA, Cullen J, Mishra P, Ali A, Milliman E, Rodrigues LO, Chen EY, Tolstikov V, Zhang L, Panagopoulos K, Shah P, Chen Y, Petrovics G, Rosner IL, Sesterhenn IA, McLeod DG, Granger E, Sarangarajan R, Akmaev V, Srinivasan A, Srivastava S, Narain NR, Dobi A.
J Transl Med. 18(1): 10, 2020. [ Journal Article ]