RESEARCH SUMMARY

Dr. Celiku develops and applies integrative computational approaches to better understand and treat primary brain cancers. Her research in the Translational Immunology Research Program at the Neuro-Oncology Branch (NOB) is driven by the conviction that solid computational principles that have stood the test of time are indispensable tools for tackling the complexity of precision oncology. Her research focuses are: 

1. Developing computational models to understand how genomic and epigenomic alterations affect tumor biology and behavior 
2. Developing semantic and machine learning approaches for characterizing molecular profiles of preclinical models alongside profiles of patient tumors—in order to assess how well these models recapitulate human disease, and how they can inform rational selection of therapies
3. Developing cancer patient genomic and outcomes data integration and visualization tools to facilitate data exploration for bench scientists and clinicians
4. Developing tools that enable primary brain tumor patients and their caregivers to track and manage their symptoms

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Areas of Expertise