Nallathamby  Devasahayam, B.S.

Nallathamby Devasahayam, B.S.

  • Center for Cancer Research
  • National Cancer Institute
Radiation Biology Branch


Dr. Devasahayam developed the radiofrequency (300 - 750 MHz) pulsed electron paramagnetic resonance (EPR ) imaging system currently in use in the Biophysical Spectroscopy and Imaging Section. His paper, “Parallel Coil Resonators for Time-Domain Radiofrequency Electron Paramagnetic Resonance Imaging of Biological Objects,” published in the Journal of Magnetic Resonance (142:168-76, 2000) was the first whole-body mouse EPR image and was featured on the cover.  Since then, Dr. Devasahayam has completed many software and hardware enhancements to continuously improve mouse imaging. To date, he has 8 patents in Fourier Transform EPR (FT-EPR) imaging techniques.  Efforts are now underway to scale up EPR imaging techniques for human applications.

Areas of Expertise

Radio Frequency Circuits
Electron Paramagnetic Resonance (EPR) Spectrometry And Imaging
Resonators For Imaging Applications
Pulsed EPR
Continuous Wave (CW) EPR


Selected Key Publications

Parallel coil resonators for time-domain radiofrequency electron paramagnetic resonance imaging of biological objects

Devasahayam N, Subramanian S, Murugesan R, Cook JA, Afeworki M, Tschudin RG, Mitchell JB, and Krishna MC.
J Magn Reson. 142: 168-76, 2000. [ Journal Article ]

Evaluation of a high-speed signal-averager for sensitivity enhancement in radio frequency Fourier transform electron paramagnetic resonance

Devasahayam N, Murugesan R, Yamada K, Reijnders K, Mitchell J, Subramanian S, Krishna M, and Cook J.
Rev Sci Instrum. 73: 3920-25, 2002. [ Journal Article ]

Tailored sinc pulses for uniform excitation and artifact-free radio frequency time-domain EPR imaging

Devasahayam N, Murugesan R, Matsumoto K, Mitchell JB, Cook JA, Subramanian S, and Krishna MC.
J Magn Reson. 168: 110-7, 2004. [ Journal Article ]

Strategies for improved temporal and spectral resolution in in vivo oximetric imaging using time-domain EPR

Devasahayam N, Subramanian S, Murugesan R, Hyodo F, Matsumoto K, Mitchell JB, and Krishna MC.
Magn Reson Med. 57: 776-83, 2007. [ Journal Article ]

A novel programmable pulse generator with nanosecond resolution for pulsed electron paramagnetic resonance applications

Devasahayam N, Subramanian S, and Krishna M.
Rev Sci Instrum. 79(2 Pt 1): 26106, 2008. [ Journal Article ]