Masaki  Terabe, Ph.D.

Masaki Terabe, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Neuro-Oncology Branch


Dr. Terabe is an extensively trained immunologist that seeks to understand the mechanisms of immune regulation in cancer patients. He hopes to elucidate the mechanisms that drive the immune system to fail to eliminate a tumor, and how we can use those findings to therapeutically drive the immune system to become act more effectively against the tumor (called immunotherapy). Current research ideas in his lab include a focus on natural killer T-cells (NKT cells), a lesser known population of the immune system which have the response rate of the innate immune system but the antigen specificity of the adaptive immune system. They are a unique component that can be recruited to tumors to attack and/or help other immune cells to destroy malignant cells, and Dr. Terabe hopes to translate his knowledge on NKT-cells to new cancer treatments that can help patients combat brain tumors more effectively.

Areas of Expertise

1) immunotherapy, 2) cancer, 3) tumor immunology, 4) glioblastoma, 5) natural killer T-cells (NKTs)


Selected Recent Publications

Making a Cold Tumor Hot: The Role of Vaccines in the Treatment of Glioblastoma

Frederico, F.C., Hancock, J.C., Brettschneider, E.E.S., Ratnam, N.M., Gilbert, M.R., Terabe, M.
Frontiers in Oncology. 11: 2021. [ Journal Article ]

Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank.

Chuntova, P., Chow, F., Watchmaker, P.B., Galvez, M., Heimberger, A.B., Newell, E.W., Diaz, A., DePinho, R.A., Li, M.O., Wherry, E.J., Mitchell, D., Terabe, M., Wainwright, D.A., Berzofsky, J.A., Herold-Mende, C., Heath, J.R., Lim, M., Margolin, K.A., Chiocca, E.A., Kasahara, N., Ellingson, B.M., Brown, C.E., Chen, Y., Fecci, P.E., Reardon, D.A., Dunn, G.P., Liau, L.M., Costello, J.F., Wick, W., Cloughesy, T., Timmer, W.C., Wen, P.Y., Prins, R.M., Platten, M., Okada, H.
Neuro-Oncology. 23(3): 356–375, 2021. [ Journal Article ]

MerTK inhibition decreases immune suppressive glioblastoma-associated macrophages and neoangiogenesis in glioblastoma microenvironment.

Su, Y.T., Butler, M., Zhang, M., Song,H., Hwang, L., Tran, A.D., Bash, R.E., Schorzman, A.N., Pang, Y., Yu, G., Zamboni, W.C., Wang, X., Frey, S.V., Miller, C.R., Maric, D., Terabe, M., Gilbert, M.R., Earp III, H.S., Wu, J.
Journal of Neuro-Oncology Advances. 2(1): 2020. [ Journal Article ]

Another layer of immune complication in glioblastoma: ICOS-ICOL.

Terabe, M., Gilbert, M.R.
Neuro-Oncology. 22(3): 305–306, 2020. [ Journal Article ]

Structure-Function Implications of the Ability of Monoclonal Antibodies Against α-Galactosylceramide-CD1d Complex to Recognize β-Mannosylceramide Presentation by CD1d.

Clark, K., Yau, J., Bloom, A., Wang, J., Venzon, D.J., Suzuki, M., Pasquet, L., Compton, B.J., Cardell., S.L., Porcelli, S.A., Painter, G.F., Zajonc, D.M., Berzofsky, J.A., Terabe, M.
Frontiers in Immunology. 2019. [ Journal Article ]

Job Vacancies

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Postdoctoral Fellow (Visiting)
Taijun Hana, M.D., Ph.D.
Postdoctoral Fellow (Visiting)
Ayaka Hara, Ph.D.
Postdoctoral Fellow (CRTA)
Guzal Khayrullina, Ph.D.
Senior Research Assistant
Hye Kyung Kim, Ph.D.
Predoctoral Fellow (OXCAM)
Emily Steffke