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Martin W. Brechbiel, Ph.D.

Martin W. Brechbiel, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Radiation Oncology Branch

RESEARCH SUMMARY

Dr. Brechbiel is a leading authority on the development of the chemistry required for effective targeted radiation therapy and imaging chemistry. His studies led to the initiation of multiple clinical trials, including those employing α-emitters 213Bi and 212Pb. His basic coordination chemistry studies also addressed the synthesis and in vivo validation of novel agents and were translated from pre-clinical studies to clinical use and onward to commercial products for both imaging and therapy of cancer.

Areas of Expertise

1) radiochemistry 2) conjugation chemistry 3) targeted radiation therapy 4) imaging 5) α-emitter therapy 6) nanotechnology