Jonathan H. Badger, Ph.D.

Jonathan H. Badger, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute


Dr. Badger's research focuses on computationally integrating genomic, transcriptomic, and phylogenetic information from microbes and their hosts in order to obtain insights into the role the microbiome plays in disease, particularly in relation to cancer. Dr, Badger is also interested in the role predatory bacteria (Bdellovibrio and relatives) play in the environment and as members of the microbiota.

Areas of Expertise

Microbial Ecology


Selected Publications

Laboratory mice born to wild mice have natural microbiota and model human immune responses

Rosshart SP, Herz J, Vassallo BG, Hunter A, Wall MK, Badger JH, McCulloch JA, Anastasakis DG, Sarshad AA, Leonardi I, Collins N, Blatter JA, Han SJ, Tamoutounour S, Potapova S, Foster St Claire MB, Yuan W, Sen SK, Dreier MS, Hild B, Hafner M, Wang D, Iliev ID, Belkaid Y, Trinchieri G, Rehermann B.
Science. 365(6452): Epub ahead of print (Aug. 2), 2019. [ Journal Article ]

An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis

Fatkhullina AR, Peshkova IO, Dzutsev A, Aghayev T, McCulloch JA, Thovarai V, Badger JH, Vats R, Sundd P, Tang HY, Kossenkov AV, Hazen SL, Trinchieri G, Grivennikov SI, Koltsova EK.
Immunity. 49(5): 943-957, 2018. [ Journal Article ]

Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance

Rosshart SP, Vassallo BG, Angeletti D, Hutchinson DS, Morgan AP, Takeda K, Hickman HD, McCulloch JA, Badger JH, Ajami NJ, Trinchieri G, Pardo-Manuel de Villena F, Yewdell JW, Rehermann B.
Cell. 171(5): 1015-1028.e13, 2017. [ Journal Article ]

Microbiome as an Immunological Modifier

Kumar M, Singh P, Murugesan S, Vetizou M, McCulloch J, Badger JH, Trinchieri G, Al Khodor S.
Methods Mol Biol. 2055: 595-638, 2020. [ Journal Article ]

Microbes and Cancer

Dzutsev A, Badger JH, Perez-Chanona E, Roy S, Salcedo R, Smith CK, Trinchieri G.
Annu Rev Immunol. 35: 199-228, 2017. [ Journal Article ]