Jennifer A. Kanakry, M.D.
- Center for Cancer Research
- National Cancer Institute
- Building 10-CRC, Room 4-3132
- Bethesda, MD 20892
Dr. Jennifer Kanakry engages in clinical research related to allogeneic hematopoietic cell transplantation for patients with hematologic malignancies and inherited and acquired disorders of the immune system. Transplant is potentially curative for these patients and Dr. Kanakry’s research is aimed at finding novel ways to make transplant less toxic, more effective, and more available to patients with these diseases. Dr. Kanakry also focuses her clinical research on viral complications of transplant and the kinetics of immune reconstitution. Dr. Kanakry leads several clinical trials at the NCI of allogeneic hematopoietic cell transplantation and of virus-specific cytotoxic T cell therapies, with a focus on peripheral T cell lymphomas and hematologic malignancies in patients living with HIV.
Areas of Expertise
Allogeneic hematopoietic cell transplantation is a potentially curative therapy for patients with disorders of the blood and immune system. Dr. Kanakry’s research is focused on clinical trials for patients with acquired or inherited disorders of the immune system and patients with hematologic malignancies requiring allogeneic hematopoietic cell transplantation. Dr. Kanakry’s work studies novel transplant platforms with the aim of improving outcomes for patients by reducing the intensity of transplant, using less than perfectly matched donors, and exploring methods to optimize immune reconstitution and cancer control after transplant. She also investigates viral complications of transplant, including clinical trials of virus-specific cytotoxic T cell therapies.
International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome
Prospective Study of a Novel, Radiation-Free, Reduced-Intensity Bone Marrow Transplantation Platform for Primary Immunodeficiency Diseases
Outcomes of Related and Unrelated Donor Searches Among Patients with Primary Immunodeficiency Diseases Referred for Allogeneic Hematopoietic Cell Transplantation
Cytomegalovirus Infection Incidence and Risk Factors Across Diverse Hematopoietic Cell Transplantation Platforms Using a Standardized Monitoring and Treatment Approach: A Comprehensive Evaluation from a Single Institution
The clinical significance of EBV DNA in the plasma and peripheral blood mononuclear cells of patients with or without EBV diseases
Jennifer A. Kanakry, M.D.
Dr. Jennifer Kanakry is a Senior Clinician and clinical researcher at the Center for Cancer Research of the National Cancer Institute. Dr. Kanakry received her B.A. (2002) from Pomona College in Claremont, California, where she studied cognitive neuropsychology and biology. She went on to receive her medical degree (2007) from a joint program between Dartmouth College School of Medicine (Hanover, NH) and Brown University School of Medicine (Providence, RI). She completed both her residency training in Internal Medicine (2007-2010) and fellowship training (2010-2013) in Hematology at Johns Hopkins Hospital. Her clinical research during fellowship was focused on virus-associated cancers, hematologic malignancies in patients living with HIV, and allogeneic hematopoietic cell transplantation for lymphoma under the mentorship of Dr. Richard Ambinder. In 2013, she joined the faculty at Johns Hopkins within the Departments of Medicine and Oncology, where she primarily focused on treating patients with diseases that more commonly occur in the setting of immunodeficiency, including lymphoma, disorders of immune dysregulation, and virus-associated lymphoproliferative disorders. In 2015, she joined the Experimental Transplantation and Immunotherapy Branch of the National Cancer Institute as an Associate Research Physician, where she focused her clinical research on optimizing approaches to allogeneic hematopoietic cell transplantation for hematologic malignancies and immunodeficiencies. In 2017, her clinical trial and patient was one of 4 features in the Discovery Channel docuseries “First in Human” Link: Discovery Documentary First in Human. In 2021, she became the Program Director for the NIH Hematology Oncology Fellowship Program, overseeing one of the largest Heme/Onc fellowship programs in the U.S. Link: NIH Hematology Oncology Fellowship.In 2022 , she became a Senior Clinician with the Center for Immuno-Oncology (CIO).