Janusz W. Koscielniak, Ph.D.
- Center for Cancer Research
- National Cancer Institute
- Building 538, Room 187
- Frederick, MD 21702-1201
- 301-846-5213
- 301-846-6231
- koscieja@mail.nih.gov
RESEARCH SUMMARY
Dr. Janusz Koscielniak manages operations of the Center for Structural Biology (CSB) NMR Facility for Biological Research.
Areas of Expertise
1) User support and training 2) NMR spectrometer hardware and software maintenance and upgrades 3) RF and microwave electronics troubleshooting and repairs 4) High vacuum and cryogenic systems operations 5) Spectrometer computer administration
Research
The NMR Facility for Biological Research provides instrumentation and required support to investigators conducting research on protein and RNA structure determination, protein-protein interactions and dynamics. The facility operates five high-field NMR spectrometers configured for bio-NMR research: state-of-the-art Bruker Avance III spectrometers equipped with cryoprobes at 850Mhz, 800MHz, 700MHz, two 600MHz and one 500MHz automated general access spectrometer configured to serve wide range of users. Facility staff also provide technical and software support to two other open access NMR facilities located within the Chemical Biology Laboratory and the Molecular Targets Laboratory, which both operate high-throughput NMR spectrometers configured for small molecule type experiments.
Biography
Janusz W. Koscielniak, Ph.D.
Dr. Janusz Koscielniak received his Ph.D. in 1982 from Wroclaw University of Science and Technology, Department of Electronics, (Poland) for pioneering work on fast imaging methods using Electron Paramagnetic Resonance (EPR). This research was continued after joining the In-Vivo EPR Laboratory at the Department of Chemistry at Ohio State University. In 1995 he joined the SAIC contract (now Leidos Biomedical Research) continuing in-vivo EPR research at CCR's Radiation Biology Branch and simultaneously supporting the expanding NMR facility. Currently, he is focused entirely on managing the CSB's NMR Facility for Biological Research.