National Cancer Institute - Cancer.gov

Gatikrushna Panigrahi, Ph.D.

Gatikrushna Panigrahi, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Research Fellow
Laboratory of Human Carcinogenesis

RESEARCH SUMMARY

Gatikrushna Panigrahi is an experienced biomedical scientist with research expertise in tumor biology, cell and molecular biology. His work focuses on investigating the impact of comorbidities, such as diabetes and hyperglycemia, on tumor biology. He has utilized xenograft models, patient tumor analyses, and in vitro studies to unravel the intricate relationship between diabetes and cancer. Notably, he has conducted multi-omics studies, including global transcriptomics, metabolomics, cytokine profiling, and whole-exome sequencing, to identify gene and metabolite signatures associated with diabetes-related breast cancer.

Areas of Expertise

Tumor Biology
Breast Cancer
Diabetes
Cancer Health Disparities

Publications

Selected Publications

Diabetes-associated breast cancer is molecularly distinct and shows a DNA damage repair deficiency

Panigrahi G, Candia J, Dorsey TH, Tang W, Ohara Y, Byun JS, Minas TZ, Zhang A, Ajao A, Cellini A, Yfantis HG, Flis AL, Mann D, Ioffe O, Wang XW, Liu H, Loffredo CA, Napoles AM, and Ambs S.
JCI Insight. 8(23): 2023. [ Journal Article ]

How Comorbidities Shape Cancer Biology and Survival

Panigrahi G, and Ambs S.
Trends Cancer . 7(6): 488-95, 2021. [ Journal Article ]

Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry.

Harris AR*, Panigrahi G*, Liu H*, Koparde VN, Bailey-Whyte M, Dorsey TH, Yates CC, and Ambs S.

(* Contributed equally.)
Cancer Res Commun . 3(10): 2014-29 , 2023. [ Journal Article ]