Chennan Li

Chennan Li, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Genitourinary Malignancies Branch


Dr. Chennan Li is interested in understanding how cancer heterogeneity is formed temporally and spatially and how this knowledge informs clinical decision-making. He is utilizing the power of multiregion sequencing and single-cell techniques to identify distinct tumor subclones and various other cells and decipher how they contribute to disease progression.

Areas of Expertise

Cell Biology
Single-cell RNA-seq Analysis


Selected Key Publications

One toolkit to bring them all, and in silico analyze them

Chennan Li, Anna Baj, Adam G. Sowalsky
Clinical and Translational Discovery.
Full-Text Article
[ Journal Article ]

Loss of KMT5C Promotes EGFR Inhibitor Resistance in NSCLC via LINC01510-Mediated Upregulation of MET

Arpita S Pal, Alejandra Agredo, Nadia A Lanman, Jihye Son, Ikjot Singh Sohal, Manvir Bains, Chennan Li, Jenna Clingerman, Kayla Gates, Andrea L Kasinski
Cancer Research. 2022.
Full-Text Article
[ Journal Article ]

InVivo Cancer-Based Functional Genomics

Chennan Li, Andrea L Kasinski
Trends in Cancer. 2020.
Full-Text Article
[ Journal Article ]

Identification and validation of microRNAs that synergize with miR-34a - a basis for combinatorial microRNA therapeutics

Esteban A Orellana, Chennan Li, Alexa Lisevick, Andrea L Kasinski
Cell Cycle. 2019.
Full-Text Article
[ Journal Article ]