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Chennan Li

Chennan Li, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Prostate Cancer Genetics Section

RESEARCH SUMMARY

Dr. Chennan Li is interested in understanding how cancer heterogeneity is formed temporally and spatially and how this knowledge informs clinical decision-making. He is utilizing the power of multiregion sequencing and single-cell techniques to identify distinct tumor subclones and various other cells and decipher how they contribute to disease progression.

Areas of Expertise

1) Genetics; 2) Cell biology; 3) Single-cell RNA-seq analysis

Publications

Selected Key Publications

Loss of KMT5C Promotes EGFR Inhibitor Resistance in NSCLC via LINC01510-Mediated Upregulation of MET

Arpita S Pal, Alejandra Agredo, Nadia A Lanman, Jihye Son, Ikjot Singh Sohal, Manvir Bains, Chennan Li, Jenna Clingerman, Kayla Gates, Andrea L Kasinski
Cancer Research. 2022.
Full-Text Article
[ Journal Article ]

InVivo Cancer-Based Functional Genomics

Chennan Li, Andrea L Kasinski
Trends in Cancer. 2020.
Full-Text Article
[ Journal Article ]

Identification and validation of microRNAs that synergize with miR-34a - a basis for combinatorial microRNA therapeutics

Esteban A Orellana, Chennan Li, Alexa Lisevick, Andrea L Kasinski
Cell Cycle. 2019.
Full-Text Article
[ Journal Article ]