Arun Kumar Ganesan, Ph.D.

Arun Kumar Ganesan, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute


Arun is studying the role of oncogenic long non-coding RNAs in mislocalizing centromere-specific protein CENP-A to ectopic sites and its impact on chromosome stability in cancer cells. His research particularly focuses on chromosome 8q24 locus that is a frequent chromosome breakpoint and translocation-prone region in several cancers.

Areas of Expertise

1) cancer biology, 2) non-coding RNAs, 3) epigenetics


Selected Key Publications

Oncogenic lncRNAs alter epigenetic memory at a fragile chromosomal site in human cancer cells

Arunkumar, Ganesan., Baek, Songjoon., Sturgill, David., Bui, Minh., & Dalal, Yamini
Science Advances. Vol 8, Issue 9: 2022.
Full-Text Article
[ Journal Article ]

Centromeric Transcription: A Conserved Swiss-Army Knife

Arunkumar G, Melters DP.
Genes. 11(8): 911, 2020. [ Journal Article ]

LncRNA OIP5-AS1 is overexpressed in undifferentiated oral tumors and integrated analysis identifies as a downstream effector of stemness-associated transcription factors

Arunkumar G, Anand S, Raksha P, Dhamodharan S, Prasanna Srinivasa Rao H, Subbiah S, Murugan AK, Munirajan AK.
Sci Rep. 8(1): 7018, 2018. [ Journal Article ]

Comprehensive analysis of aberrantly expressed lncRNAs and construction of ceRNA network in gastric cancer

Arun K, Arunkumar G, Bennet D, Chandramohan SM, Murugan AK, Munirajan AK.
Oncotarget. 9(26): 18386-18399, 2018. [ Journal Article ]

Dysregulation of miR-200 family microRNAs and epithelial-mesenchymal transition markers in oral squamous cell carcinoma

Arunkumar G, Deva Magendhra Rao AK, Manikandan M, Prasanna Srinivasa Rao H, Subbiah S, Ilangovan R, Murugan AK, Munirajan AK.
Oncol Lett. 5(1): 649-657, 2018. [ Journal Article ]