Armando  Filie, M.D.

Armando Filie, M.D.

  • Center for Cancer Research
  • National Cancer Institute
Laboratory of Pathology


Dr. Filie has promoted the utilization of new ancillary techniques and well-established ancillary tests in the diagnosis of cancer and other diseases in cytology. His recent studies have demonstrated that minute amounts of cytology material are sufficient for detecting EGFR and KRAS mutation and diagnosing cytomegalovirus infection. Dr. Filie also oversees the clinical research efforts of the Cytopathology Section, Laboratory of Pathology, which centers around the application of emerging molecular techniques to cytology where conventional processing methods and well-established ancillary techniques fall short in providing sufficient information for an accurate cytologic diagnosis.

Areas of Expertise

Fine Needle Aspiration
Thyroid Cytology
Melanoma Cytology


Selected Recent Publications

Viral, immunologic, and clinical features of primary effusion lymphoma

Lurain K, Polizzotto MN, Aleman K, Bhutani M, Wyvill KM, Gon├žalves PH, Ramaswami R, Marshall VA, Miley W, Steinberg SM, Little RF, Wilson W, Filie AC, Pittaluga S, Jaffe ES, Whitby D, Yarchoan R, Uldrick TS.
Blood. 133(16): 1753-1761, 2019. [ Journal Article ]

A randomized, placebo-controlled, double-blinded, crossover trial of pioglitazone for severe asthma

Kaler M, Barochia AV, Weir NA, Cuento RA, Stylianou M, Roth MJ, Filie AC, Vaughey EC, Nathan SD, Levine SJ.
J Allergy Clin Immunol. 140(6): 1716-1718, 2017. [ Journal Article ]

High-Throughput Microdissection for Next-Generation Sequencing

Rosenberg AZ, Armani MD, Fetsch PA, Xi L, Pham TT, Raffeld M, Chen Y, O'Flaherty N, Stussman R, Blackler AR, Du Q, Hanson JC, Roth MJ, Filie AC, Roh MH, Emmert-Buck MR, Hipp JD, Tangrea MA.
PLoS One. 11(3): e0151775, 2016. [ Journal Article ]

An Improved Breast Epithelial Sampling Method for Molecular Profiling and Biomarker Analysis in Women at Risk for Breast Cancer

Danforth DN, Warner AC, Wangsa D, Ried T, Duelli D, Filie AC, Prindiville SA.
Breast Cancer (Auckl). 9: 31-40, 2015. [ Journal Article ]

Breast implant-associated anaplastic large cell lymphoma in a patient with Li-Fraumeni syndrome

Lee YS, Filie A, Arthur D, Fojo AT, Jaffe ES.
Histopathology. 67(6): 925-7, 2015. [ Journal Article ]


Cytotechnologist (Contr.)
Keith Brosky, B.S., CT-ASCP
Dana Erickson
May Owens
Clinical Fellow
Helmae Mulatu Wubneh, M.D.