RESEARCH SUMMARY

Dr. Roschke main research focus is elucidation of mechanisms of chromosomal instability in cancer. Her work on interrogation of the NCI drug discovery panel for drugs and chemical compounds targeting chromosomally unstable cells resulted in identification of specific groups of chemical compounds with elevated cytotoxic activity toward more karyotypically rearranged and/or chromosomally unstable cancer cells.

She has extensive expertise in cancer molecular cytogenetics and provides technical help and training for  fluorescent microscopy techniques: human and mouse spectral karyotyping (SKY), FISH with interphase nuclei and metaphase chromosomes.

Areas of Expertise