National Cancer Institute - Cancer.gov

Peter L. Choyke, M.D., F.A.C.R.

Peter L. Choyke, M.D., F.A.C.R.

  • Center for Cancer Research
  • National Cancer Institute
  • Building 10, Room B3B69F
  • Bethesda, MD 20892-1088
  • 240-760-6093
  • pchoyke@nih.gov
Chief
Molecular Imaging Branch
Senior Investigator
Head, Imaging Section

RESEARCH SUMMARY

Dr. Choyke directs the Molecular Imaging Branch. His research interests include the translation of molecular imaging methods, such as MRI, optical and radionuclide/PET into the clinic. His primary clinical focus is on imaging, diagnosis and therapy of prostate cancer. In the lab, Dr. Choyke focuses on understanding uptake of various PET agents, including PSMA, at the genomic level. In addition, his lab works on the development of new imaging methods for cancer including cell labeling with PET agents, and imaging the tumor microenvironment including immune markers.

Areas of Expertise

Imaging Cancer (Cellular and Clinical)
Diagnostics and Biomarkers
Prostate Cancer
Cell Tracking
Radiopharmaceutical Development
Lymphatic Imaging

Information for Patients

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Publications

Selected Recent Publications

Can Molecular Imaging Measure T-cell Activation?

Choyke PL.
Cancer Res. 80(14): 2975-76, 2020. [ Journal Article ]

Evaluating Biochemically Recurrent Prostate Cancer: Histologic Validation of 18F-DCFPyL PET/CT with Comparison to Multiparametric MRI

Lindenberg L, Mena E, Turkbey B, Shih JH, Reese SE, Harmon SA, Lim I, Lin F, Ton A, McKinney YL, Eclarinal P, Citrin DE, Dahut W, Madan R, Wood BJ, Krishnasamy V, Chang R, Levy E, Pinto P, Eary JF, Choyke PL.
Radiology. [Epub ahead of print - July 7], 2020. [ Journal Article ]

Standardized Nomenclature and Surveillance Methodologies After Focal Therapy and Partial Gland Ablation for Localized Prostate Cancer: An International Multidisciplinary Consensus

Lebastchi AH, George AK, Polascik TJ, Coleman J, de la Rosette J, Turkbey B, Wood BJ, Gorin MA, Sidana A, Ghai S, Tay KJ, Ward JF, Sanchez-Salas R, Muller BG, Malavaud B, Mozer P, Crouzet S, Choyke PL, Ukimura O, Rastinehad AR, Pinto PA.
Eur Urol. [Epub ahead of print - June 9], 2020. [ Journal Article ]

Neoadjuvant PROSTVAC prior to radical prostatectomy enhances T-cell infiltration into the tumor immune microenvironment in men with prostate cancer

Abdul Sater H, Marté JL, Donahue RN, Walter-Rodriguez B, Heery CR, Steinberg SM, Cordes LM, Chun G, Karzai F, Bilusic M, Harmon SA, Turkbey IB, Choyke PL, Schlom J, Dahut WL, Madan RA, Pinto PA, Gulley JL.
J Immunother Cancer. 8(1): e000655, 2020. [ Journal Article ]

MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis

Ahdoot M, Wilbur AR, Reese SE, Lebastchi AH, Mehralivand S, Gomella PT, Bloom J, Gurram S, Siddiqui M, Pinsky P, Parnes H, Linehan WM, Merino M, Choyke PL, Shih JH, Turkbey B, Wood BJ, Pinto PA.
New Engl J Med. 382(10): 917-28, 2020. [ Journal Article ]

Job Vacancies

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Team

Research Physicist (Contr.)
Stephen S. Adler, Ph.D.
Research Physicist (Contr.)
Michael V. Green
Research Physicist (Contr.)
Jurgen Seidel, Ph.D.
Research Associate III (Contr.)
Gary Leonard Griffiths, Ph.D.
Stadtman Investigator
Stephanie Harmon, Ph.D.
Adjunct Investigator
Paula M. Jacobs, Ph.D.
Special Volunteer
Jorge Carrasquillo, M.D.
Research Collaborator
Ethan Bergvall, M.D.
Clinical Research Nurse
Yolanda L. McKinney, B.S.N., R.N.
Data Manager
Anita Ton
Program Coordinator (Contr.)
Juanita Weaver
Patient Care Technician
Linda Burke Prout
Biologist
Colleen Olkowski, B.S.
MRI Technologist (Contr.)
Dagane Daar, M.S. RT
profile picture
IT Data Manager
Philip C. Eclarinal, B.S.
MRI Technologist (Contr.)
Hoa Tieu, RT (R)(CT)(MR), CNMT, PET
Nuclear Medicine Technologist (Contr.)
Mona Cedo, B.S., CNMT
Technical Laboratory Manager
Karen Wong, M.S.
Nuclear Medicine Technologist (Contr.)
Joseph Carreon, A.A.S., CNMT
Nuclear Medicine Technologist (Contr.)
Brynn Leonard, B.S., R.T.(N)(CT), CNMT

Alumni

Anna Brown
Anna Brown
2014-2015
MRSP student
Iclal Ocak
Iclal Ocak
2006-2007
Post-doctoral Fellow
Tristan Barrett
Tristan Barrett
2005-2007
Post-doctoral Fellow
Baris Turkbey
Baris Turkbey
2007-2012
Post-doctoral Fellow
Greg Ravizzini
Greg Ravizzini
2007-2009
Post-doctoral Fellow
Esther Mena-Gonzalez
Esther Mena-Gonzalez
2011-2013
Post-doctoral Fellow
Vinita Alexander
Vinita Alexander
2011-2012
HHMI Research Scholar
Frank Kuo
Frank Kuo
2012-2013
MRSP student
Osama Elbuluk
Osama Elbuluk
2013-2014
MRSP student
Sandeep Sankineni
Sandeep Sankineni
2014-2015
Post-doctoral Fellow
Jason McKellop
Jason McKellop
2003-2004
Post-doctoral Fellow
Cesar Castro
Cesar Castro
2003-2004
Post-doctoral Fellow

News

News

Testing with combined biopsy method improves prostate cancer diagnosis in NCI study

March 4, 2020
NCI Press Release

A method of testing for prostate cancer developed at the National Cancer Institute (NCI) leads to more accurate diagnosis and prediction of the course of the disease, according to a large study. Learn more...

Smarter Prostate Cancer Diagnosis

CCR Milestones 2020

CCR researchers have developed new artificial intelligence tools that will help radiologists improve prostate cancer diagnosis. Learn more...

Seeing Prostate Cancer More Clearly

CCR Milestones 2017

A new imaging method enables sensitive detection and monitoring of high-risk prostate cancers. Learn more...