The runt-related transcription factor 1 (RUNX1) gene regulates the formation of blood cells. People with mutations in the gene are at risk of bleeding and have a higher risk of developing cancers of the blood. A clinical trial led by Lea C. Cunningham, M.D., Associate Research Physician in the Immune Deficiency Cellular Therapy Program, is researching a drug for RUNX1 mutations.
The trial will take place at the NIH Clinical Center in Bethesda, Maryland, and there is no cost for participation.
For more information, please contact Rebecca Alexander at (240) 781-4037 or email@example.com
Clinicaltrials.gov identifier: NCT06090669
NCI Protocol ID: IRB001542
Official Title: Phase Ib Study of Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency
The Center for Cancer Research is NCI’s internal cancer center, a publicly funded organization working to improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care. Highly trained physician-scientists develop and carry out clinical trials to create the medicines of tomorrow, treating patients at the world’s largest dedicated research hospital on the campus of the National Institutes of Health in Bethesda, Maryland.