The Liver Cancer Program regularly publishes in peer-reviewed journals on the early detection, diagnosis, prognosis, treatment, natural history and health disparities of liver cancer. You can find our papers on each topic below.
A Viral Exposure Signature Defines Early Onset of Hepatocellular Carcinoma.
Liu J, Tang W, Budhu A, Forgues M, Hernandez MO, Candia J, Kim Y, Bowman ED, Ambs S, Zhao Y, Tran B, Wu X, Koh C, Surana P, Liang TJ, Guarnera M, Mann D, Rajaure M, Greten TF, Wang Z, Yu H, Wang XW.
Cell. 182(2):317-328, 2020.
Electromagnetic Tracking and Optical Molecular Imaging Guidance for Liver Biopsy and Point-of-Care Tissue Assessment in Phantom and Woodchuck Hepatocellular Carcinoma.
de Ruiter QMB, Xu S, Li M, Pritchard WF, Starost MF, Filie A, Mikhail AS, Mauda-Havakuk M, Esparza-Trujillo JA, Bakhutashvili I, Heidari P, Mahmood U, Karanian JW, Wood BJ.
Cardiovascular Interventional Radiology. 2021 May 21. doi: 10.1007/s00270-021-02853-x. Epub ahead of print. PMID: 34021380
Non-proteolytic ubiquitin modification of PPARγ by Smurf1 protects the liver from steatosis.
Zhu K, Tang Y, Xu X, Dang H, Tang LY, Wang X, Wang XW, Zhang YE.
PLoS Biol. Dec 19;16(12): e3000091, 2018.
Mechanisms of hepatic stellate cell activation.
Tsuchida T, Friedman SL.
Nat Rev Gastroenterol Hepatol. Jul;14(7):397-411, 2017.
Analysis of long noncoding RNA expression in hepatocellular carcinoma of different viral etiology.
Zhang Q, Matsuura K, Kleiner DE, Zamboni F, Alter HJ, Farci P.
J Transl Med. Nov 28;14(1):328, 2016.
Single-cell biology uncovers apoptotic cell death and its spatial organization as a potential modifier of tumor diversity in HCC.
Khatib SA, Ma L, Dang H, Forgues M, Chung JY, Ylaya K, Hewitt SM, Chaisaingmongkol J, Rucchirawat M, Wang XW.
Hepatology. 2022 Sep;76(3):599-611. doi: 10.1002/hep.32345. Epub 2022 Feb 10.PMID: 35034369
Bile acid-activated macrophages promote biliary epithelial cell proliferation through integrin alphavbeta6 upregulation following liver injury.
Guillot A, Guerri L, Feng D, Kim SJ, Ahmed YA, Paloczi J, He Y, Schuebel K, Dai S, Liu F, Pacher P, Kisseleva T, Qin X, Goldman D, Tacke F, Gao B.
J Clin Invest. 2021 May 3;131(9):e132305. doi: 10.1172/JCI132305
Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma.
Ma L, Wang L, Khatib SA, Chang CW, Heinrich S, Dominguez DA, Forgues M, Candia J, Hernandez MO, Kelly M, Zhao Y, Tran B, Hernandez JM, Davis JL, Kleiner DE, Wood BJ, Greten TF, Wang XW.
J Hepatol. 2021 Jun 30:S0168-8278(21)01848-1. doi: 10.1016/j.jhep.2021.06.028. Online ahead of print.
Understanding the Cause and Consequence of Tumor Heterogeneity.
Khatib, S, Yotsawat, P, Hien, D, Wang XW.
Trends in Cancer. Apr;6(4) 267-271, 2020.
Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer.
Ma L, Hernandez MO, Zhao Y, Mehta M, Tran B, Kelly M, Rae Z, Hernandez JM, Davis JL, Martin SP, Kleiner DE, Hewitt SM, Ylaya K, Wood BJ, Greten TF, Wang XW.
Cancer Cell. Oct 14;36(4):418-430, 2019.
MicroRNA-223 ameliorates nonalcoholic steatohepatitis and cancer by targeting multiple inflammatory and oncogenic genes in hepatocytes.
He, Y., Hwang, S., Cai, Y., Kim, S., Xu, M., Yang, D., Guillot, A., Feng, D., Seo, W., Gao, B.
Hepatology 2019, 70:1150-1167
ALDH2 deficiency promotes alcohol-associated liver cancer by transferring harmful DNA via exosomes and activating oncogenic pathways. Seo, W., Gao, Y., He, Y., Sun, J., Xu, H., Feng, D., Park, S., Cho, Y., Guillot, A., Ren, T., Wu, R., Wang, J., Kim, S., Hwang, S., Liangpunsakul, S., Yang, Y., Niu, J., Gao, B.
Journal of Hepatology 2019, 71:1000-1011.
Single-cell analysis reveals cancer stem cell heterogeneity in hepatocellular carcinoma.
Zheng H, Pomyen Y, Hernandez MO, Li C, Livak F, Tang W, Dang H, Greten TF, Davis JL, Zhao Y, Mehta M, Levin Y, Shetty J, Tran B, Budhu A, Wang XW.
Hepatology. Jul;68(1):127-140, 2018.
Hepatic Hippo signaling inhibits pro-tumoral microenvironment to suppress hepatocellular carcinoma.
Kim, W., Khan, S. K., Liu, Y., Xu, R., Park, O., Cha, B., Gao, B., Yang, Y.
Gut 2018, 67(9):1692-1703
Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma.
Chaisaingmongkol J, Budhu A, Dang H, Rabibhadana S, Pupacdi B, Kwon SM, Forgues M, Pomyen Y, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul CU, Sricharunrat T, Phornphutkul K, Sangrajrang S, Cam M, He P, Hewitt SM, Ylaya K, Wu X, Andersen JB, Thorgeirsson SS, Waterfall JJ, Zhu YJ, Walling J, Stevenson HS, Edelman D, Meltzer PS, Loffredo CA, Hama N, Shibata T, Wiltrout RH, Harris CC, Mahidol C, Ruchirawat M, Wang XW. TIGER-LC Consortium.
Cancer Cell. Jul 0;32(1):57-70.e3, 2017.
Hippo signaling interactions with Wnt/b-catenin and Notch signaling repress liver tumorigenesis.
Kim, W., Khan S., Gvozdenovic-Jeremic, J., Kim, Y., Dahlman1, J., Kim, H., Park, P., Ishitani, T., Jho, E., Gao, B., Yang, Y.
Journal of Clinical Investigation 2017;127:137-152
Transcriptional Induction of Periostin by a Sulfatase 2-TGFβ1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma.
Chen G, Nakamura I, Dhanasekaran R, Iguchi E, Tolosa EJ, Romecin PA, Vera RE, Almada LL, Miamen AG, Chaiteerakij R, Zhou M, Asiedu MK, Moser CD, Han S, Hu C, Banini BA, Oseini AM, Chen Y, Fang Y, Yang D, Shaleh HM, Wang S, Wu D, Song T, Lee JS, Thorgeirsson SS, Chevet E, Shah VH, Fernandez-Zapico ME, Roberts LR.
Cancer Res. Feb 1;77(3):632-645, 2017.
DNAJB1-PRKACA fusion kinase interacts with b-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma.
Kastenhuber ER, Lalazar G, Houlihan SL, Tschaharganeh DF, Baslan T, Chen CC, Requena D, Tian S, Bosbach B, Wilkinson JE, Simon SM, Lowe SW.
Proc. Natl. Acad. Sci. U.S.A. 114: 13076-13084, 2017.
Telomere Length and Survival of Patients with Hepatocellular Carcinoma in the United States.
Yang B, Shebl FM, Sternberg LR, Warner AC, Kleiner DE, Edelman DC, Gomez A, Dagnall CL, Hicks BD, Altekruse SF, Hernandez BY, Lynch CF, Meltzer PS, McGlynn KA.
PLoS One. Nov 23;11(11):e0166828, 2016.
A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection.
Zhang DY, Goossens N, Guo J, Tsai MC, Chou HI, Altunkaynak C, Sangiovanni A, Iavarone M, Colombo M, Kobayashi M, Kumada H, Villanueva A, Llovet JM, Hoshida Y, Friedman SL.
Gut. Oct;65(10):1754-64, 2016.
Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo.
Porat-Shliom N, Tietgens AJ, Van Itallie CM, Vitale-Cross L, Jarnik M, Harding OJ, Anderson JM, Gutkind JS, Weigert R, Arias IM.
Hepatology. Oct;64(4):1317-29, 2016.
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.
Tschaharganeh DF, Xue W, Calvisi DF, Evert M, Michurina TV, Dow LE, Banito A, Katz SF, Kastenhuber ER, Weissmueller S, Huang CH, Lechel A, Andersen JB, Capper D, Zender L, Longerich T, Enikolopov G, Lowe SW.
Cell. Jul 31;158(3):579-92, 2014. Erratum in: Cell. Jun 2;165(6):1546-154, 2016.
The expression of phospho-AKT, phospho-mTOR, and PTEN in extrahepatic cholangiocarcinoma.
Chung JY, Hong SM, Choi BY, Cho H, Yu E, Hewitt SM.
Clinical Cancer Research. Jan 15;15(2):660-7, 2009.
Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy.
Budhu, A., Pehrsson, E.C., He, A., Goyal, L., Kelley, R.K., Dang, H., Xie, C., Monge, C., Tandon, M., Ma, L., Revsine, M., Kuhlman, L., Zhang, K., Baiev, I., Lamm, R., Patel, K., Kleiner, D.E., Hewitt, S.M., Tran, B., Shetty, J., Wu, X., Zhao, Y., Shen, T-W., Choudhari, S., Kriga, Y., Ylaya, K., Warner, A.C., Edmondson, E.F., Forgues, M., Greten, T.F., and Wang, X.W.
Cell Reports Medicine, May 23, 2023. DOI:https://doi.org/10.1016/j.xcrm.2023.101052
Innate lymphoid cells and innate-like T cells in cancer - at the crossroads of innate and adaptive immunity.
Ruf B, Greten TF, Korangy F.
Nat Rev Cancer. 2023 Apr 20. doi: 10.1038/s41568-023-00562-w. PMID: 37081117
Immunology and immunotherapy of cholangiocarcinoma.
Greten TF, Schwabe R, Bardeesy N, Ma L, Goyal L, Kelley RK, Wang XW.
Nat Rev Gastroenterol Hepatol. 2023 Jan 25. doi: 10.1038/s41575-022-00741-4. PMID: 36697706
Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD. Ma C, Fu Q, Diggs LP, McVey JC, McCallen J, Wabitsch S, Ruf B, Brown Z, Heinrich B, Zhang Q, Rosato U, Wang S, Cui L, Berzofsky JA, Kleiner DE, Bosco DB, Wu LJ, Lai CW, Rotman Y, Xie C, Korangy F, Greten TF.
Cancer Cell. 2022 Sep 12;40(9):986-998.e5. doi: 10.1016/j.ccell.2022.08.004. Epub 2022 Sep 1.PMID: 36055226
Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer. Ma L, Heinrich S, Wang L, Keggenhoff FL, Khatib S, Forgues M, Kelly M, Hewitt SM, Saif A, Hernandez JM, Mabry D, Kloeckner R, Greten TF, Chaisaingmongkol J, Ruchirawat M, Marquardt JU, Wang XW.
Nat Commun 13, 7533 (2022). https://doi.org/10.1038/s41467-022-35291-5
Intestinal MYC modulates obesity-related metabolic dysfunction.
Luo Y, Yang S, Wu X, Takahashi S, Sun L, Cai J, Krausz KW, Guo X, Dias HB, Gavrilova O, Xie C, Jiang C, Liu W, Gonzalez FJ.
Nature Metabolism. 2021 Jul;3(7):923-939. doi: 10.1038/s42255-021-00421-8. Epub 2021 Jul 1.PMID: 34211180
Imaging, Pathology, and Immune Correlates in the Woodchuck Hepatic Tumor Model.
Mauda-Havakuk M, Mikhail AS, Starost MF, Jones EC, Karim B, Kleiner DE, Partanen A, Esparza-Trujillo JA, Bakhutashvili I, Wakim PG, Kassin MT, Lewis AL, Karanian JW, Wood BJ, Pritchard WF.
Journal of Hepatocellular Carcinoma. 2021 Mar 9;8:71-83. doi: 10.2147/JHC.S287800. PMID: 33728278; PMCID: PMC7955744.
Myelocytomatosis-Protein Arginine N-Methyltransferase 5 Axis Defines the Tumorigenesis and Immune Response in Hepatocellular Carcinoma.
Luo Y, Gao Y, Liu W, Yang Y, Jiang J, Wang Y, Tang W, Yang S, Sun L, Cai J, Guo X, Takahashi S, Krausz KW, Qu A, Chen L, Xie C, Gonzalez FJ.
Hepatology. 2021 Apr 25. doi: 10.1002/hep.31864. Online ahead of print.PMID: 33896016
Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma.
Zhang Q, Ma C, Duan Y, Heinrich B, Rosato U, Diggs LP, Ma L, Roy S, Fu Q, Brown ZJ, Wabitsch S, Thovarai V, Fu J, Feng D, Ruf B, Cui LL, Subramanyam V, Frank KM, Wang S, Kleiner DE, Ritz T, Rupp C, Gao B, Longerich T, Kroemer A, Wang XW, Ruchirawat M, Korangy F, Schnabl B, Trinchieri G, Greten TF.
Cancer Discovery. 2021 May;11(5):1248-1267. doi: 10.1158/2159-8290.CD-20-0304. Epub 2020 Dec 15.PMID: 33323397
CD40-mediated immune cell activation enhances response to anti-PD-1 in murine intrahepatic cholangiocarcinoma.
Diggs LP, Ruf B, Ma C, Heinrich B, Cui L, Zhang Q, McVey JC, Wabitsch S, Heinrich S, Rosato U, Lai W, Subramanyam V, Longerich T, Loosen SH, Luedde T, Neumann UP, Desar S, Kleiner D, Gores G, Wang XW, Greten TF.
J Hepatology. 2021 May;74(5):1145-1154. doi: 10.1016/j.jhep.2020.11.037. Epub 2020 Dec 1.PMID: 33276030
Understanding tumour cell heterogeneity and its implication for immunotherapy in liver cancer using single-cell analysis.
Heinrich S, Craig AJ, Ma L, Heinrich B, Greten TF, Wang XW.
J Hepatology. 2021 Mar;74(3):700-715. doi: 10.1016/j.jhep.2020.11.036. Epub 2020 Nov 30.PMID: 33271159
Drug-eluting embolic microspheres: State-of-the-art and emerging clinical applications.
Mikhail AS, Negussie AH, Mauda-Havakuk M, Owen JW, Pritchard WF, Lewis AL, Wood BJ.
Expert Opinion Drug Delivery 2021 Jan 22:1-16. Doi: 10.1080/17425247.2021.1835858. Online ahead of print. PMID: 33480306
Synthesis, characterization, and imaging of radiopaque bismuth beads for image-guided transarterial embolization.
Negussie AH, de Ruiter QMB, Britton H, Donahue DR, Boffi Q, Kim YS, Pritchard WF, Moonen C, Storm G, Lewis AL, Wood BJ.
Scientific Reports. 2021 Jan 12;11(1):533. doi: 10.1038/s41598-020-79900-z. PMID: 33436734
Engineered Anti-GPC3 Immunotoxin, HN3-ABD-T20, Produces Regression in Mouse Liver Cancer Xenografts Through Prolonged Serum Retention.
Fleming BD, Urban DJ, Hall MD, Longerich T, Greten TF, Pastan I, Ho M.
Hepatology. 2020 May;71(5):1696-1711. doi: 10.1002/hep.30949. Epub 2020 Jan 27.PMID: 31520528 Free PMC article.
Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice.
Li D, Li N, Zhang Y-F, Fu H, Feng M, Schneider D, Su L, Wu X, Zhou J, Mackay S, Kramer J, Duan Z, Yang H, Kolluri A, Hummer AM, Torres MB, Zhu H, Hall MD, Luo X, Chen J, Wang Q, Abate-Daga D, Dropublic B, Hewitt SM, Orentas RJ, Greten TF, Ho M.
Gastroenterology. Jun;158(8):2250-2265, 2020.
Glypican-3-Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.
Fu Y, Urban DJ, Nani RR, Zhang YF, Li N, Fu H, Shah H, Gorka AP, Guha R, Chen L, Hall MD, Schnermann MJ, Ho M.
Hepatology. 2019 Aug;70(2):563-576. doi: 10.1002/hep.30326. Epub 2019 Feb 19.PMID: 30353932 Free PMC article.
Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells.
Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, Agdashian D, Terabe M, Berzofsky JA, Fako V, Ritz T, Longerich T, Theriot CM, McCulloch JA, Roy S, Yuan W, Thovarai V, Sen SK, Ruchirawat M, Korangy F, Wang XW, Trinchieri G, Greten TF.
Science. May 25;360(6391), 2018.
ONC201 kills breast cancer cells in vitro by targeting mitochondria.
Greer YE, Porat-Shliom N, Nagashima K, Stuelten C, Crooks D, Koparde VN, Gilbert SF, Islam C, Ubaldini A, Ji Y, Gattinoni L, Soheilian F, Wang X, Hafner M, Shetty J, Tran B, Jailwala P, Cam M, Lang M, Voeller D, Reinhold WC, Rajapakse V, Pommier Y, Weigert R, Linehan WM, Lipkowitz S.
Oncotarget. Apr 6;9(26):18454-18479, 2018.
Tumor-Specific Zr-89 Immuno-PET Imaging in a Human Bladder Cancer Model.
Escorcia FE, Steckler JM, Abdel-Atti D, Price EW, Carlin SD, Scholz WW, Lewis JS, Houghton JL.
Mol Imaging Biol. Mar 5; [Epub ahead of print], 2018.
An unbiased in vivo functional genomics screening approach in mice identifies novel tumor cell-based regulators of immune rejection.
Shuptrine CW, Ajina R, Fertig EJ, Jablonski SA, Kim Lyerly H, Hartman ZC, Weiner LM.
Cancer Immunol Immunother. Dec;66(12):1529-1544, 2017.
Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression.
Eggert T, Wolter K, Ji J, Ma C, Yevsa T, Klotz S, Medina-Echeverz J, Longerich T, Forgues M, Reisinger F, Heikenwalder M, Wang XW, Zender L, Greten TF.
Cancer Cell. Oct 10;30(4):533-547, 2016.
First Human Experience with Directly Image-able Iodinated Embolization Microbeads.
Levy EB, Krishnasamy VP, Lewis AL, Willis S, Macfarlane C, Anderson V, van der Bom IM, Radaelli A, Dreher MR, Sharma KV, Negussie A, Mikhail AS, Geschwind JF, Wood BJ.
Cardiovascular Interventional Radiology. 2016 Aug;39(8):1177-86 PMID: 27206503
A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.
Dauch D, Rudalska R, Cossa G, Nault JC, Kang TW, Wuestefeld T, Hohmeyer A, Imbeaud S, Yevsa T, Hoenicke L, Pantsar T, Bozko P, Malek NP, Longerich T, Laufer S, Poso A, Zucman-Rossi J, Eilers M, Zender L.
Nature Medicine. Jul;22(7):744-53, 2016.
Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signaling and protein synthesis.
Gao W, Tang Z, Zhang YF, Feng M, Qian M, Dimitrov DS, Ho M.
Nature Communications. Mar 11; 6:6536, 2015.
c-Abl modulates tumor cell sensitivity to antibody-dependent cellular cytotoxicity.
Murray JC, Aldeghaither D, Wang S, Nasto RE, Jablonski SA, Tang Y, Weiner LM.
Cancer Immunol Res. Dec;2(12):1186-98, 2014.
Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma.
Feng M, Gao W, Wang R, Chen W, Man YG, Figg WD, Wang XW, Dimitrov DS, Ho M.
Proc Natl Acad Sci U S A. Mar 19;110(12):E1083-91, 2013.
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Kang TW, Yevsa T, Woller N, Hoenicke L, Wuestefeld T, Dauch D, Hohmeyer A, Gereke M, Rudalska R, Potapova A, Iken M, Vucur M, Weiss S, Heikenwalder M, Khan S, Gil J, Bruder D, Manns M, Schirmacher P, Tacke F, Ott M, Luedde T, Longerich T, Kubicka S, Zender L.
Nature. Nov 9;479(7374):547-51, 2011.
Selective killing of tumor neovasculature paradoxically improves chemotherapy delivery to tumors.
Escorcia FE, Henke E, McDevitt MR, Villa CH, Smith-Jones P, Blasberg RG, Benezra R, Scheinberg DA.
Cancer Research. Nov 15;70(22):9277-86, 2010.
Dissecting liver tumor heterogeneity to improve health equity
Ma, L and Wang, XW.
Trends in Cancer. 2022, Apr;8(4):286-290.
Immunologic Markers and Risk of Hepatocellular Carcinoma in HBV- and HCV-infected Individuals.
Koshiol J, Argirion I, Liu Z, Lam T, O'Brien TR, Yu K, McGlynn KA, Petrick JL, Pinto L, Hildesheim A, Pfeiffer R, Lee M, Yang HI.
Alimentary Pharmacology & Therapeutics 2021;54(6):833-842. Epub 2021/07/19. doi: 10.1111/apt.16524.
Integrative molecular characterization of gallbladder cancer reveals microenvironment-associated subtypes.
Nepal C, Zhu B, O'Rourke CJ (co-first authors), Bhatt DK, Lee D, Song L, Wang D, Van Dyke A, Choo-Wosoba H, Liu Z, Hildesheim A, Goldstein AM, Dean M, LaFuente-Barquero J, Lawrence S, Mutreja K, Olanich ME, Bermejo JL, Group CGRES, Ferreccio C, Roa JC, Rashid A, Hsing AW, Gao YT, Chanock SJ, Araya JC, Andersen JB, Koshiol J (co-last authors).
Journal of Hepatology. 2021;74(5):1132-1144. Epub 2020/12/05. doi: 10.1016/j.jhep.2020.11.033.
Associations between reproductive factors and biliary tract cancers in women from the Biliary Tract Cancers Pooling Project.
Jackson SS, Adami HO, Andreotti G, Beane-Freeman LE, de Gonzalez AB, Buring JE, Fraser GE, Freedman ND, Gapstur SM, Gierach G, Giles GG, Grodstein F, Hartge P, Jenab M, Kirsh V, Knutsen SF, Lan Q, Larsson SC, Lee IM, Lee MH, Liao LM, Milne RL, Monroe KR, Neuhouser ML, O'Brien KM, Petrick JL, Purdue MP, Rohan TE, Sandin S, Sandler DP, Sawada N, Shadyab AH, Simon TG, Sinha R, Stolzenberg-Solomon R, Tsugane S, Weiderpass E, Wolk A, Yang HI, Zheng W, McGlynn KA, Campbell PT, Koshiol J.
Journal of Hepatology. 2020;73(4):863-72. Epub 2020/05/22. doi: 10.1016/j.jhep.2020.04.046.
Association Between Aspirin Use and Biliary Tract Cancer Survival.
Jackson SS, Pfeiffer RM, Liu Z, Anderson LA, Tsai HT, Gadalla SM, Koshiol J.
JAMA Oncology. 2019. Epub 2019/10/18. doi: 10.1001/jamaoncol.2019.4328.
Statin use and reduced risk of biliary tract cancers in the UK Clinical Practice Research Datalink.
Liu Z, Alsaggaf R, McGlynn KA, Anderson LA, Tsai HT, Zhu B, Zhu Y, Mbulaiteye SM, Gadalla SM, Koshiol J.
Gut. 2019;68(8):1458-64. Epub 2018/11/19. doi: 10.1136/gutjnl-2018-317504.
Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma.
Chaisaingmongkol J, Budhu A, Dang H, Rabibhadana S, Pupacdi B, Kwon SM, Forgues M, Pomyen Y, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul CU, Sricharunrat T, Phornphutkul K, Sangrajrang S, Cam M, He P, Hewitt SM, Ylaya K, Wu X, Andersen JB, Thorgeirsson SS, Waterfall JJ, Zhu YJ, Walling J, Stevenson HS, Edelman D, Meltzer PS, Loffredo CA, Hama N, Shibata T, Wiltrout RH, Harris CC, Mahidol C, Ruchirawat M, Wang XW. TIGER-LC Consortium.
Cancer Cell. Jul 0;32(1):57-70.e3, 2017.
Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma.
Cancer Genome Atlas Research Network.
Cell. Jun 15;169(7):1327-1341.e23, 2017.