Murali Palangat Ph.D.

Murali Palangat Ph.D.
Research Biologist
Senior Research Assistant

Team Member of:

My two primary research areas of interest are (i) understanding the structure-function of splicing factor U2AF-RNA interactions during translation and how its regulation controls gene expression and, (ii) how the cancer associated splicing factor mutations alter RNA fate leading to control of gene expression and their role in cancer biology.

Areas of Expertise

1. Biochemistry and Molecular Biology. 2. Single molecule transcription. 3. In vivo live cell imaging.

Contact Info

Murali Palangat Ph.D.
Center for Cancer Research
National Cancer Institute
Building 41, Room B303
Bethesda, MD 20892
Ph: 240-760-6692
Fax: 240-541-4450

Selected Publications

  1. Palangat M, Anastasakis DG, Fei DL, Lindblad KE, Bradley R, Hourigan CS, Hafner M, Larson DR
    Genes and Development. DOI: 10.1101/gad.319590.118: 2019. [ Journal Article ]
  2. The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription.
    Navdeep Malik, Hualong Yan, Nellie Moshkovich, Murali Palangat, Howard Yang, Vanesa Sanchez, Zhuo Cai, Tyler J. Peat, Shunlin Jiang, Chengyu Liu, Maxwell Lee, Beverly A. Mock, Stuart H. Yuspa, Daniel Larson, Lalage M. Wakefield & Jing Huang
    Nature Communications. 10: 2071-2086, 2019. Full-Text Article [ Journal Article ]
  3. Palangat M and Larson DR
    Methods “RNA Structure Determination”. 2016. [ Journal Article ]
  4. Coulon A, Ferguson ML, de Turris V, Palangat M, Chow CC, Larson DR
    Elife. 2014. [ Journal Article ]
  5. Windgassen TA, Mooney RA, Nayak D, Palangat M, Zhang J, Landick R
    Nucl. Acids Res. 42: 12707-12721, 2014. [ Journal Article ]