Structure of hRpn2-bound hRpn13 with K48-diubiquitin. hRpn13 Pru (periwinkle blue), hRpn2 (940-953) (light orange) and the bound proximal ubiquitin (yellow) of K48-diubiquitin are shown as a ribbon and surface diagrams. The full conformational ensemble is displayed for unbound distal ubiquitin (green) of K48-diubiquitin with each conformer as a transparent ribbon diagram (PDB: 6UYI) (X. Lu et al. Structure 28, 495-506 e493, doi:10.1016/j.str.2020.02.007 (2020).

Structure of hRpn13 Pru complexed with K48-diUb and the hRpn2 C-terminus.