View a listing of the CSB-NMR facility publication history.
2022
Maiti A, Hedger AK, Myint W, Balachandran V, Watts JK, Schiffer CA, Matsuo H. Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state. Nat Commun. 2022 Nov 19;13(1):7117. doi: 10.1038/s41467-022-34752-1. PMID: 36402773; PMCID: PMC9675756.
Myint W, Schiffer CA, Matsuo H. HIV-1 VIF and human APOBEC3G interaction directly observed through molecular specific labeling using a new dual promotor vector. J Magn Reson. 2022 Jun;339:107230. doi: 10.1016/j.jmr.2022.107230. Epub 2022 Apr 26. PMID: 35550909; PMCID: PMC9149140.
Chen, X.$, Mirazee, J. M. $, Skorupka, K. A., Matsuo, H., Youkharibache, P.*, Taylor, N.*, Walters, K. J.*. The CD8a hinge is intrinsically disordered with a dynamic exchange that includes proline cis-trans isomerization. Journal of Magnetic Resonance (2022) 340:107234. doi: 10.1016/j.jmr.2022.107234. PMID: 35617919 *, co-corresponding author; $, co-first author
Chao, F.A., Dharmaiah, S., Taylor, T., Messing, S., Gillette, W., Esposito, D., Nissley, D.V., McCormick, F., Byrd, R.A., Simanshu, D.K., and Cornilescu, G. (2022). Insights into the Cross Talk between Effector and Allosteric Lobes of KRAS from Methyl Conformational Dynamics. J Am Chem Soc 144, 4196-4205. 10.1021/jacs.2c00007.
2021
Hou S, Lee JM, Myint W, Matsuo H, Kurt Yilmaz N, Schiffer CA. Structural basis of substrate specificity in human cytidine deaminase family APOBEC3s. J Biol Chem. 2021 Aug;297(2):100909. doi: 10.1016/j.jbc.2021.100909. Epub 2021 Jun 24. PMID: 34171358; PMCID: PMC8313598.
Lu, X., Sabbasani, V.R., Osei-Amponsa, V., Evans, C. N., King, J. C., Tarasov, S. G., Dyba, M., Chan, K. C., Schwieters, C. D., Choudhari, S., Fromont, C., Zhao, Y., Tran, B. Chen, X., Matsuo, H. Andresson, T., Chari, R., Swenson, R. E., Tarasova, N. I., and Walters, K. J.: Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma, bioRxiv, doi:https://doi.org/10.1101/2021.07.16.452547 (2021); Nat. Commun. (2021) 12:7318 https://doi.org/10.1038/s41467-021-27570-4.
2020
Maiti A, Myint W, Delviks-Frankenberry KA, Hou S, Kanai T, Balachandran V, Sierra Rodriguez C, Tripathi R, Kurt Yilmaz N, Pathak VK, Schiffer CA, Matsuo H. Crystal Structure of a Soluble APOBEC3G Variant Suggests ssDNA to Bind in a Channel that Extends between the Two Domains. J Mol Biol. 2020 Nov 20;432(23):6042-6060. doi: 10.1016/j.jmb.2020.10.020. Epub 2020 Oct 22. PMID: 33098858; PMCID: PMC7771068.
Soubias, O., Pant, S., Heinrich, F., Zhang, Y., Roy, N.S., Li, J., Jian, X., Yohe, M.E., Randazzo, P.A., Losche, M., et al. (2020). Membrane surface recognition by the ASAP1 PH domain and consequences for interactions with the small GTPase Arf1. Sci Adv 6. 10.1126/sciadv.abd1882.
2019
Ding, J., Swain, M., Yu, P., Stagno, J. R., Wang, Y. X. Conformational flexibility of adenine riboswitch aptamer in apo and bound states using NMR and an X-ray free electron laser. J. Biomol. NMR., Sep;73(8-9):509-518, 2019. PMID: 31606878 PMCID: PMC6817744
Biancospino, M., Buel, G. R., Niño, C. A., Maspero, E., di Perrotolo, R. S., Raimondi, A., Redlingshöfer, L., Weber, J., Brodsky, F. M.*, Walters, K. J.*, Polo, S.* Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension. Nature Communications, 10(1):4974, 2019. doi: 10.1038/s41467-019-12855-6. *co-corresponding. PMID: 31672988 PMCID: PMC6823378
Chao, F.-A., Li, Y., Zhang, Y., Byrd, R.A. Probing the broad time scale and heterogeneous conformational dynamics in the catalytic core of the Arf-GAP ASAP1 via methyl adiabatic relaxation dispersion. J. Am. Chem. Soc., 141(30):11881-11891, 2019. PMID: 31293161
Solomon, W.C., Myint, W., Hou, S., Kanai, T., Tripathi, R., Yilmaz, N.K., Schiffer, C.A., Matsuo H. Mechanism for APOBEC3G catalytic exclusion of RNA and non-substrate DNA. Nucleic Acids Research, 47(14):7676-7689, 2019. PMID: 31424549 PMCID: PMC6698744
2018
Liu, Y., Holmstrom, E., Yu, P., Tan, K., Zuo, X., Nesbitt, D. J., Sousa, R., Stagno, J. R., Wang, Y. X. Incorporation of isotopic, fluorescent, and heavy-atom-modified nucleotides into RNAs by position-selective labeling of RNA. Nat Protoc., May;13(5):987-1005, 2018. PMID: 29651055
Calabrese, D. R., Chen, X., Leon, E., Gaikwad, S., Phyo, Z., Hewitt, W. M., Alden, S., Hilimire, T. A., He, F., Michalowski, A. M., Simmons, J. K., Saunders, L. B., Zhang, S., Connors, D., Walters, K. J.*, Mock, B. A.*, Schneekloth, J. S. Jr.* Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex. Nature Communications, 9:4229, 2018. doi: 10.1038/s41467-018-06315-w. *co-corresponding. PMID: 30315240 PMCID: PMC6185959
Maiti A, Myint W, Kanai T, Delviks-Frankenberry K, Sierra Rodriguez C, Pathak VK, Schiffer CA, Matsuo H. Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA. Nature Communications, Jun 25;9(1):2460, 2018. PMID: 29941968 PMCID: PMC6018426