Breadcrumb

E. Michael Gertz, Ph.D.

E. Michael Gertz, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute

RESEARCH SUMMARY

E. Michael Gertz is a computational biologist working on cancer genomics, biological sequence analysis and cancer immunology.

Areas of Expertise

Computational Biology And Bioinformatics
Sequence Analysis
Algorithms
Cancer Genomics
Sequence Analysis
Numerical Analysis

Publications

Selected Key Publications

FISHtrees 3.0: Tumor Phylogenetics Using a Ploidy Probe

Gertz EM, Chowdhury SA, Lee WJ, Wangsa D, Heselmeyer-Haddad K, Ried T, Schwartz R, and Schäffer AA.
PloS One. 11(6): e0158569, 2016. [ Journal Article ]

PSEUDOMARKER 2.0: efficient computation of likelihoods using NOMAD

Gertz EM, Hiekkalinna T, Digabel SL, Audet C, Terwilliger JD, and Schäffer AA.
BMC Bioinformatics. 15: 47, 2014. [ Journal Article ]

Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity

Lopez-Herrera G, Tampella G, Pan-Hammarström Q, Herholz P, Trujillo-Vargas CM, Phadwal K, Simon AK, Moutschen M, Etzioni A, Mory A, Srugo I, Melamed D, Hultenby K, Liu C, Baronio M, Vitali M, Philippet P, Dideberg V, Aghamohammadi A, Rezaei N, Enright V, Du L, Salzer U, Eibel H, Pfeifer D, Veelken H, Stauss H, Lougaris V, Plebani A, Gertz EM, Schäffer AA, Hammarström L, and Grimbacher B.
Am J Hum Genet. 90(6): 986-1001, 2012. [ Journal Article ]

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor

Glocker EO, Kotlarz D, Boztug K, Gertz EM, Schäffer AA, Noyan F, Perro M, Diestelhorst J, Allroth A, Murugan D, Hätscher N, Pfeifer D, Sykora KW, Sauer M, Kreipe H, Lacher M, Nustede R, Woellner C, Baumann U, Salzer U, Koletzko S, Shah N, Segal AW, Sauerbrey A, Buderus S, Snapper SB, Grimbacher B, and Klein C.
N Engl J Med. 361(21): 2033-45, 2009. [ Journal Article ]

Composition-based statistics and translated nucleotide searches: improving the TBLASTN module of BLAST

Gertz EM, Yu YK, Agarwala R, Schäffer AA, and Altschul SF.
BMC Biol. 4: 41, 2006. [ Journal Article ]