CCR Animal Resource Program


The CCR Animal Resource Program plans, develops, and coordinates laboratory animal resources for CCR’s research programs. We also provide training, imaging, and technology development in support of moving basic discoveries to the clinic.

The ARP Office:

  • Coordinates the use of animal holding space within NCI facilities, NIH central facilities, and shared facilities
  • Oversees the use of all centrally funded animal resources
  • Assists with cost-effective options for animal technical support
  • Coordinates/negotiates animal-related interagency agreements and memoranda of understanding
  • Serves as liaison to the NCI project officer, the NIH Division of Veterinary Resources, and program staff
  • Provides advice on working with animals and assists with animal study protocol development
  • Provides site visit animal resource documents

Requirements for Conducting an Animal Study


  • Complete NIH approved training courses
  • Register with the Animal Exposure Surveillance Program
  • Obtain approval from the NCI Animal Care and Use Committee (ACUC) for the proposed study
  • Complete safety registration of  human cells/tissue, pathogens, recombinant nucleic acid molecules and receive IBC approval for use in animal research 
  • Obtain approval to use animal holding space from the CCR Animal Resource Program Office
  • Complete facility specific instruction in animal facility operating procedures

News & Announcements

  • 2020 NIH Betheda AAALAC Site Visit announced - June 15-19, 2020 

  • NCI at Frederick ACUC - launched new electronic Animal Study Protocol (ASP) system, Topaz Elements in  December 2019. 

  • NCI's Patient-Derived Models Repository (PDMR)  - This is a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs), in vitro patient-derived tumor cell cultures (PDCs) and cancer associated fibroblasts (CAFs) as well as patient-derived organoids (PDOrg). Histologies include urothelial, squamous cell lung, renal, colon, pancreatic, prostate, adult soft tissue sarcoma, breast, melanoma plus  others. See the PDMR website (https://pdmr.cancer.gov) for more details. 


Contact Information

Mary Custer
Associate Director, Animal Resource Program 
240.760.7747
custema@mail.nih.gov

Kathy Divi
Scientific Program Analyst
240.760.7749
kathy.divi@nih.gov

Mailing Address:

Animal Resource Program
Center for Cancer Research
NCI, NIH, DHHS
Building 31 Room 3A11
31 Center Drive
Bethesda, MD 20892-2440