Hoyoung M. Maeng, M.D.

Hoyoung M. Maeng, M.D.
Assistant Research Physician
Vaccine Branch
Director, Clinical Trials Team

Team Member of:

Jay A. Berzofsky, M.D., Ph.D.

Dr. Maeng’s research interests focus on therapeutic vaccines in cancer as well as novel strategies to treat precancerous lesions in patients with chronic viral infection. She believes that the essence of the Center for Cancer Research, NCI is the "bench-to-bedside" exemplfied by the vaccine that was created here at NCI to treat patients in the NIH Clinical Center. She leads the clinical trials team in the Vaccine Branch as a clinical PI.

Areas of Expertise
1) therapeutic vaccine, 2) cancer immunotherapy, 3) clinical trial

Contact Info

Hoyoung M. Maeng, M.D.
Center for Cancer Research
National Cancer Institute
Building 10, Room 4A22
Bethesda, MD 20814
Ph: 240-781-3253
hoyoung.maeng@nih.gov

Dr. Maeng's clinical research involves therapeutic vaccines to harness a patient's own immune system to fight against cancer or chronic infections. The Vaccine Branch clinical team is exploring various strategies to broaden cancer treatment options with lower toxicity customized to individuals.

NIH Scientific Focus Areas:
Cancer Biology, Clinical Research

Selected Key Publications

  1. Cancer vaccines: translation from mice to human clinical trials.
    Hoyoung Maeng - Center for Cancer Research Masaki Terabe - Center for Cancer Research Jay A Berzofsky
    Current Opnion in Immunology. 51: 111-122, 2018. [ Journal Article ]
  2. Mechanism of Fas signaling regulation by human herpesvirus 8 K1 oncoprotein .
    Berkova Z, Wang S, Wise JF, Maeng H, Ji Y, Samaniego F.
    J. Natl. Cancer Inst. 101(6): 399-411, 2009. [ Journal Article ]
  3. K1 protein of human herpesvirus 8 suppresses lymphoma cell Fas-mediated apoptosis.
    Wang S, Wang S, Maeng H, Young DP, Prakash O, Fayad LE, Younes A, Samaniego F.
    Blood. 109(5): 2174-82, 2007. [ Journal Article ]

Dr. Maeng graduated from Yonsei University College of Medicine, Seoul, South Korea with an M.D. in 1998. She started her first research project in Yonsei Cancer Center as a medical student where she first developed an interest in translational medicine. She completed her residency in internal medicine followed by a fellowship in hematology and oncology at Severance Hospital, Yonsei University. Further training at the Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center as a research fellow in 2005 provided her with a deeper insight into the understanding of viral oncoprotein and cancer. Based on the work done at that time, she was awarded the AACR-MedImmune Fellowship in 2007. After serving in the public health system for Korean National Insurance as a physician treating patients with hematologic malignancies, she returned to the U.S. and completed her internal medicine residency at MetroWest Medical Center, Framingham, MA.  She then completed a leukemia fellowship at the University of Texas MD Anderson Cancer Center, followed by a fellowship in medical oncology at NCI.

Name Position
Lee England P.A. Physician Assistant
Santhana Webb R.N., O.C.N. Research Nurse
Giselle Martinez Data Manager (Contr.)
Grace Jin Special Volunteer