Stephen M. Hewitt, M.D., Ph.D.
- Center for Cancer Research
- National Cancer Institute
- Bldg 10, Rm 3N252
- Bethesda, MD 20892-1500
- 240-760-6290
- hewitts@mail.nih.gov
RESEARCH SUMMARY
The Experimental Pathology Laboratory (EPL) is focused on translational pathology research. The EPL focuses on collaborative research projects within the Laboratory of Pathology, as well as provides core laboratory support. Areas of expertise within the EPL include: histology, immunohistochemistry, tissue microarray construction and application, micro-dissection technologies, in situ assays for RNA and DNA, whole slide imaging, image analysis and tissue proteomics.
Areas of Expertise
Research
The Experimental Pathology Laboratory (EPL) focuses on translational pathology research. The EPL focuses on collaborative research projects within the Laboratory of Pathology, as well as provides core laboratory support.
Areas of expertise with the laboratory include: histology, immunohistochemistry, tissue microarray construction and application, micro-dissection technologies, in situ assays for RNA and DNA, whole slide imaging, image analysis and tissue proteomics.
Publications
Profiling of Phospho-AKT, Phospho-mTOR, Phospho-MAPK and EGFR in Non-small Cell Lung Cancer
Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression
Expression of stress-induced phosphoprotein1 (STIP1) is associated with tumor progression and poor prognosis in epithelial ovarian cancer
Multiplex Quantitative Measurement of mRNAs From Fixed Tissue Microarray Sections
Biography
Stephen M. Hewitt, M.D., Ph.D.
Dr. Hewitt earned his MD at University of Texas Medical School at Houston, and PhD at the University of Texas Graduate School of Biomedical Sciences, completing my thesis in genetics at MD Anderson Cancer Center. He completed my residency in Anatomic Pathlogy in the Laboratory of Pathology, NCI, and is board certified in Anatomic Pathology. Dr Hewitt led the The Tissue Array Research Program (TARP Lab) from 2000-2014 and the Applied Molecular Pathology Laboratory (AMPL), a dual division (CCR and DCEG) effort from 2009 till 2014. In 2014, Dr Hewitt initiated the Experimental Pathology Laboratory, within the Laboratory of Pathology.
Dr. Hewitt is a member of the Clinical Laboratory Standards Institute Immunology & Ligand Assay Consensus Committee, and serves as co-chair of the Subcommittee on Immunohistochemical Assays and a consultant to the Hematology and Pathology Devices Panel, Center for Devices and Radiological Health, Food and Drug Administration. Dr Hewitt has co-authored more than 225 articles and servers on the editorial board of four peer-reviewed journals.
