Constance M. Yuan, M.D., Ph.D.

Constance M. Yuan, M.D., Ph.D.
Associate Research Physician
Laboratory of Pathology
Deputy Head, Flow Cytometry Laboratory

Team Member of:

Maryalice Stetler-Stevenson, M.D., Ph.D.

Dr. Yuan received her M.D and Ph.D. from Jefferson Medical College in Philadelphia, PA. She completed her clinical pathology training at the University of Pennsylvania, and her anatomic pathology and hematopathology training at the University of Florida in Gainesville FL, where she also served as faculty. She joined the NCI Flow Cytometry Unit in July 2006. Dr. Yuan seeks to advance the field of clinical multiparamenter flow cytometry specifically in hematolymphoid neoplasia, and has a special interest in the application of proliferation assessment.

Areas of Expertise

1) flow cytometry, 2) hermatolymphoid neoplasia

Contact Info

Constance M. Yuan, M.D., Ph.D.
Center for Cancer Research
National Cancer Institute
Building 10 - Magnuson CC, Room 3S235H
Bethesda, MD 20892
Ph: 301-480-8077
yuanc@mail.nih.gov

Selected Publications

  1. Flow cytometric differentiation of abnormal and normal plasma cells in the bone marrow in patients with multiple myeloma and its precursor diseases.
    Tembhare PR, Yuan CM, Venzon D, Braylan R, Korde N, Manasanch E, Zuchlinsky D, Calvo K, Kurlander R, Bhutani M, Tageja N, Maric I, Mulquin M, Roschewski M, Kwok M, Liewehr D, Landgren O, Stetler-Stevenson M.
    Leuk. Res.. 38: 371-6, 2014. [ Journal Article ]
  2. Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia.
    Haso W, Lee DW, Shah NN, Stetler-Stevenson M, Yuan CM, Pastan IH, Dimitrov DS, Morgan RA, FitzGerald DJ, Barrett DM, Wayne AS, Mackall CL, Orentas RJ.
    Blood. 121: 1165-74, 2013. [ Journal Article ]
  3. Distinguishing hairy cell leukemia variant from hairy cell leukemia: development and validation of diagnostic criteria.
    Shao H, Calvo KR, Grönborg M, Tembhare PR, Kreitman RJ, Stetler-Stevenson M, Yuan CM.
    Leuk. Res.. 37: 401-9, 2013. [ Journal Article ]
  4. Quantification of expression of antigens targeted by antibody-based therapy in chronic lymphocytic leukemia.
    Tembhare PR, Marti G, Wiestner A, Degheidy H, Farooqui M, Kreitman RJ, Jasper GA, Yuan CM, Liewehr D, Venzon D, Stetler-Stevenson M.
    Am. J. Clin. Pathol.. 140: 813-8, 2013. [ Journal Article ]
  5. Case study interpretation--Portland: Case 1. Hairy cell leukemia with CLL-like monoclonal B lymphocytosis.
    Tembhare P, Yuan CM, Xi L, Marti G, Raffeld M, Stetler-Stevenson M.
    Cytometry B Clin Cytom. 82: 177-9, 2012. [ Journal Article ]

Dr. Yuan received her M.D and Ph.D. from Jefferson Medical College in Philadelphia, PA. She completed her clinical pathology training at the University of Pennsylvania, and her anatomic pathology and hematopathology training at the University of Florida in Gainesville FL, where she also served as faculty. She joined the NCI Flow Cytometry Unit in July 2006. Dr. Yuan seeks to advance the field of clinical multiparamenter flow cytometry specifically in hematolymphoid neoplasia, and has a special interest in the application of proliferation assessment.