Jung-Eun Park, Ph.D.

Team Member of:
Dr. Park's primary research interest lies in understanding the physiological functions of two functionally distinct mammalian polo-like kinases, Plk1 and Plk4, which appear to play key roles in mitotic progression and centriole duplication, respectively. Dr. Park is also interested in developing anti-Plk1 therapeutic agents by exploiting both potential leads from our own research and from the unique resources that NCI provides to the intramural community.
kinases
Contact Info
Center for Cancer Research
National Cancer Institute
Building 37, Room 3118
Bethesda, MD 20892-4254
Ph: 240-760-7281
parkju@mail.nih.gov
Dr. Park's primary research interest lies in understanding the physiological functions of two functionally distinct mammalian polo-like kinases, Plk1 and Plk4, which appear to play key roles in mitotic progression and centriole duplication, respectively. Dr. Park is also interested in developing anti-Plk1 therapeutic agents by exploiting both potential leads from our own research and from the unique resources that NCI provides to the intramural community.
Selected Publications
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Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis.Nat Commun. 10(1): 4959, 2019. [ Journal Article ]
- Nat. Struct. Mol. 21(8): 696-703, 2014. [ Journal Article ]
- Proc. Natl. Acad. Sci. U.S.A. 108: 8200-5, 2011. [ Journal Article ]
- Nat. Chem. Biol. 7: 595-601, 2011. [ Journal Article ]
- Proc. Natl. Acad. Sci. U.S.A. 106: 1725-30, 2009. [ Journal Article ]
Dr. Jung-Eun Park joined the NIH in 2002 as an Office of International Affairs' predoctoral fellow and received her Ph.D. in 2004 from the Department of Biology at the Dong-A University, South Korea. She then obtained her postdoctoral research training at the NCI and became a staff scientist in the Laboratory of Metabolism, CCR, in 2010.