Ivy Yin, Ph.D.
Dr. Ivy Yin is a biologist in in the Laboratory of Genitourinary Cancer Pathology at the National Cancer Institute, NIH. She is interested in the cellular and molecular mechanisms of prostate cancer related bone metastasis. Her current work is focused on the role of TWEAK/Fn14 pathway, TGFβ pathway and Ras signaling pathway in the development and progression of prostate cancer metastasis to bone and brain.
1) mouse metastasis model, 2) mouse preclinical trial for anti-metastasis therapies, 3) live animal imaging, 4) metastatic bone disease
Selected Recent Publications
- Molecular Cell Biology. 35: 1940-11, 2015. [ Journal Article ]
EGF Receptor Promotes Prostate Cancer Bone Metastasis by Downregulating miR-1 and Activating TWIST1.Cancer Research. 75: 3077-86, 2015. [ Journal Article ]
- Cancer Research. 74: 4306-17, 2014. [ Journal Article ]
Cediranb /AZD2171 Inhibits Bone and Brain Metastasis in a Preclinical Model of Advanced Prostate Cancer.Cancer Research. 70: 8662-73, 2010. [ Journal Article ]
- Molecular Cell Biology. 27: 7538-50, 2007. [ Journal Article ]