Breadcrumb

picture of Paul Randazzo

Paul A. Randazzo, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Head, Section for the Study of the Arfs

RESEARCH SUMMARY

The group studies Arf family guanine nucleotide binding proteins and their regulators Arf GTPase-activating proteins (Arf GAPs) and Arf guanine nucleotide exchange factors (Arf GEFs), with a focus on their function in the regulation of integrin adhesion complexes.

Areas of Expertise

Guanine Nucleotide Binding Proteins
ADP-Ribosylation Factor Guanine Nucleotide Binding Proteins (Arfs)
GTPase-Activating Proteins (GAPs)
Guanine Nucleotide Exchange Factors (GEFs)

Publications

Selected Recent Publications

ARAP2 signals through Arf6 and Rac1 to control focal adhesion morphology

Chen P, Jian X, Yoon H, Randazzo PA.
J. Biol. Chem. 288: 5849-60, 2013. [ Journal Article ]

The ArfGAP ASAP1 Controls Actin Stress Fiber Organization via Its N-BAR Domain

Gasilina A, Vitali T, Luo R, Jian X, Randazzo PA
iScience. 22: 166-180, 2019.
Full-Text Article
[ Journal Article ]

Actin Binding to the BAR Domain and Arf GAP Activity of ASAP1 Coordinately Control Actin Stress Fibers and Focal Adhesions

Hye-Young Yoon, Jonah Unthank, Sandeep Pallikkuth, Pei-Wen Chen, Paul A Randazzo
Biology of the Cell. 117(4): e70005, 2025.
Full-Text Article
[ Journal Article ]

Job Vacancies

We have no open positions in our group at this time, please check back later.

To see all available positions at CCR, take a look at our Careers page. You can also subscribe to receive CCR's latest job and training opportunities in your inbox.

Team

Senior Research Assistant
Xiaoying Jian, Ph.D.
Post-Doctoral Fellow (CRTA)
Eric Rosenberg, Ph.D.
Scientist (Contractor)
Hye-Young Yoon, Ph.D.
Staff Scientist
Olivier Soubias, PhD

News

Learn more about CCR research advances, new discoveries and more
on our news section.