The Branch's Genomics and Pharmacology Facility manages and assesses molecular interaction data obtained through multiple platforms to increase our understanding of the effect of these interactions on the chemosensitivity of cancer and creates tools that facilitate this process. Translation of this information will be directed towards the recognition of diagnostic and therapeutic cancer biomarkers and directed cancer therapy. Learn more...
The Miner Suite of bioinformatic software packages developed by the Facility are freely available for public use. Visit the links below to learn more about each one.
The CellMiner Cross Database (CDB) enables exploration and analysis of cancer cell line pharmacogenomic data across different sources.
A database and query tool designed for the cancer research community to facilitate integration of the molecular datasets generated by the Genomic and Parmacology Facility and its collaborators on the NCI-60. Learn more...
A tool that produces Clustered Image Maps (CIMS) (i.e., clustered heat maps).
A tool that leverages the Gene Ontology (GO) database for biological interpretation of microarray data.
A tool for batch processing of multiple microarrays and integreated CIMs of the GoMiner results.
A repository of electronically navigatable Kohn Molecular Interaction Maps (MIMs).
A tool for batch-translation among many types of gene and protein identifiers.
A suite of very user-friendly tools designed for use by every bench biologist who needs to check for the impact of gene splice variation on common molecular biology technologies, including RT-PCR, RNAi, expression microarrays, and peptide-based assays.
A web application for mapping microarray probes to transcripts in an exon-specific manner.
A tool that allows users to search for appropriate, commercially available antibodies for research purposes, and to match each antibody to its respective genomic identifiers.