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Staff Scientist - Cryo-EM, Centrosome biology, Microscopy

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Job Description

The position will involve research projects aimed toward understanding the regulation of centrosome and centriole formation in healthy and transformed human cells. The staff scientist is expected to conduct research projects while also providing supervision and training to postdoctoral and postbaccalaureate fellows within the lab on cell, biochemical, and microscopy techniques used for analyzing interactions between centrosomal proteins and their localization within the centrosome. The ideal candidate will have a background in electron tomography at cryogenic and/or room temperatures, protein biochemistry, and cell biology approaches.

Specific duties and responsibilities include:

  • Conduct scientific experiments independently and in collaboration. Specifically, to design experiments, collect and analyze data, maintain clear and timely records and research notes, draw conclusions consistent with results and published literature, communicate research findings, and draft manuscripts.
  • Provide training to junior lab members in microscope operations, guidance in microscopy-related experimental design, specimen preparation and data analysis.
  • Perform microscopy and laboratory equipment troubleshooting and maintenance including communication with vendors and technicians.
  • Administrative duties including but not limited to ordering and maintaining supplies, record keeping, lab housekeeping, assistance in the development of standard operating procedures, and other similar duties as assigned by the supervisor.

Qualifications and Job Details

Degree Required
Ph.D. or equivalent
Job Location
Frederick
Appointment Type
Government Position (Salary commensurate with experience)
Work Schedule
Full-time (In-Person)
Citizenship
US Citizenship not required - (ie, permanent resident, visa)

Required and Preferred Skills

Required Skills
  • Ph.D. in life science or another related field. Three to four years of experience as a post-doctoral fellow leading and publishing independent research projects.
  • A working knowledge of microscopy fundamentals and hands-on experience (such as sample preparation, data acquisition, image analysis) with electron tomography at cryogenic and/or room temperatures.
  • Proven competence in biochemistry/protein biochemistry and cell biology approaches.
  • Ability to perform experimental work and other essential duties timely, independently, and with great attention to detail. 
  • English language proficiency with excellent verbal and written communication skills. 
  • Passion for science and to address fundamental biological questions.

About the NCI Center for Cancer Research

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Frederick

Frederick is the second largest city in Maryland but retains a “small town” feel, surrounded by mountain views with a vibrant Main Street community. The city offers outstanding schools, a balanced and thriving economy and a highly educated workforce.

How to Apply
Submit:
  • CV/Resume
  • Statement of Research Goals
  • 3 References
  • Cover Letter
  • Summary of Research Experience
  • Diversity Statement
Additional Application Information

Please include a diversity statement describing your track record of and commitment to promoting diversity, equity, and inclusion in chemistry/biochemistry research and/or medicine, including, but not limited to, the understanding of and impacting issues of equity, inclusion, and diversity, successful recruitment and/or mentorship of individuals from historically underrepresented groups, demonstrated sustained efforts to promote diversity, equity and inclusion, and plans for addressing diversity and inclusion in the future. 

Contact Information
Contact Name
Jadranka Loncarek
E-mail Address
Jadranka.Loncarek@nih.gov
DHHS, NIH and NCI are equal opportunity employers. The NCI and CCR are deeply committed to diversity of thought, equity and inclusion and encourage applications from qualified women, underrepresented minorities and individuals with disabilities.