Job Description
Our lab studies the molecular mechanisms that govern centrosome and centriole assembly in human cells. We explore how centrosome-assembly steps are coordinated with other cell cycle events and how that coordination is perturbed in pathologies. We are keenly interested in elucidating the role of Polo-like kinase 1 in centriole maturation and centrosome copy control and in understanding how centrosomes and centrosome-associated processes go awry in cancer. Our experimental approaches range from cutting-edge microscopy (light and electron), high-content transcriptomics, and biochemical and molecular biology to proteomics.
The successful candidate in this position will be part of a vibrant, collaborative, multi-disciplinary environment and outstanding research infrastructure. They will participate in ongoing, novel projects and collaborative efforts with our colleagues inside and outside NIH.
Qualifications and Job Details
Required and Preferred Skills
Applicants must have a Ph.D. in Life or Biomedical Sciences and less than two years of postdoctoral training. They must demonstrate excellence in problem-solving skills and verbal and written communication. Applicants with experience in any of the following areas are particularly encouraged to apply: Advanced light and electron imaging modalities, proteomics, transcriptomics, and cell cycle. However, outstanding candidates with broader experience in molecular and cellular biology will also be considered.
About the NCI Center for Cancer Research
The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.
Frederick
Frederick is the second largest city in Maryland but retains a “small town” feel, surrounded by mountain views with a vibrant Main Street community. The city offers outstanding schools, a balanced and thriving economy and a highly educated workforce.
Candidates interested in this position should forward their cover Letter, CV, and name/contact information of three references to Dr. Jadranka Loncarek at jadranka.loncarek@nih.gov .