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S. Perwez  Hussain, Ph.D.

S. Perwez Hussain, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute

RESEARCH SUMMARY

Dr. Hussain’s research is focused on identifying novel therapeutic targets in pancreatic cancer, which is one of the most lethal malignancies. His recent study has identified macrophage migration inhibitory factor (MIF), an inflammatory mediator, as a critical component in disease aggressiveness and a candidate therapeutic target in human pancreatic cancer. Dr. Hussain is the Head of Pancreatic Cancer Unit and his group utilizes a combination of global and targeted translational research strategies, focused on inflammatory mediators, to examine the underlying mechanisms of human pancreatic cancer progression and understand the mechanistic and functional role of a gene or pathway associated with patient’s outcome.

Areas of Expertise

1) pancreatic cancer 2) inflammatory mediators 3) macrophage migration inhibitory factor (MIF) 4) nitric oxide (NO) 5) mouse model of pancreatic cancer 6) microRNA

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