Changqing Xie, M.D., Ph.D.

Changqing Xie, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Thoracic and GI Malignancies Branch


I am interested in exploring the potential mechanism of resistance to treatment with immune checkpoint inhibitor in gastrointestinal (GI) malignancy. My focus is to dissect the role of cancer stem cells in cholangiocarcinoma in terms of developing this therapy resistance.

Areas of Expertise

Gastrointestinal (GI) Malignancy
Immune Checkpoint Inhibitors

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Selected Publications

Characterization of Immunogenicity of Malignant Cells with Stemness in Intrahepatic Cholangiocarcinoma by Single-Cell RNA Sequencing

Bian J, Fu J, Wang X, Lee J, Brar G, Escorcia FE, Cam M, XIE C
Stem Cells Int. 2022: 3558200, 2022. [ Journal Article ]

Clinical Indicators for Long-Term Survival with Immune Checkpoint Therapy in Advanced Hepatocellular Carcinoma

Monge C, Xie C, Steinberg SM, Greten TF
J Hepatocellular Carcinoma. 8: 507-512, 2021. [ Journal Article ]

Immune Checkpoint Inhibitor Associated Hepatotoxicity in Primary Liver Cancer Versus Other Cancers: A Systematic Review and Meta-Analysis

Fu J, Li W-Z, McGrath NA, Lai CW, Brar G, Xiang Y-Q, Xie C
Frontiers In Oncology. 11: 650292, 2021. [ Journal Article ]

Systemic treatment options for advanced biliary tract carcinoma

Xie C, McGrath NA, Monge Bonilla C, Fu J
Journal of Gastroenterology. 55(10): 944-957, 2020. [ Journal Article ]

Immune Checkpoint Blockade in Combination with Stereotactic Body Radiotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma

Xie C, Duffy AG, Brar G, Fioravanti S, Mabry-Hrones D, Walker M, Bonilla CM, Wood BJ, Citrin DE, Gil Ramirez EM, Escorcia FE, Redd B, Hernandez JM, Davis JL, Gasmi B, Kleiner D, Steinberg SM, Jones JC, Greten TF.
Clin Cancer Res. 26(10): 26(10):2318-26, 2020. [ Journal Article ]

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Xiao Bin Zhu


Jianyang Fu
Jianyang Fu
Nicole McGrath
Nicole McGrath
Xin Wang
Xin Wang
Postbaccalaureate Fellow (CRTA)


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