Albright et al. describe the previously unknown function of TGFβ in promoting the transition of GCB cells from LZ to DZ. The cover shows staining for phosphorylated Smad2 (red) in a Peyer’s patch from a wild-type mouse.
Lab/Branch/Program:
Lymphoid Malignancies Branch
Citation:
TGFβ signaling in germinal center B cells promotes the transition from light zone to dark zone.
Albright AR, Kabat J, Li M, Raso F, Reboldi A and Muppidi JR. J Exp Med. 216(11):2531-2545, 2019.
Albright AR, Kabat J, Li M, Raso F, Reboldi A and Muppidi JR. J Exp Med. 216(11):2531-2545, 2019.
Published Date:
November, 2019