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Staff Scientist - Cancer biology, genetics

Date Posted
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Name of Hiring Official/Investigator

Job Description

The Laboratory of Pathology, CCR, NCI, NIH, Bethesda, MD, is actively recruiting a staff scientist to work in the Cancer Molecular Pathology section headed by Frederic G. Barr, MD, PhD. This research section uses a multidisciplinary approach involving genomics and bioinformatics along with cell culture and animal models to study genetic and epigenetic alterations in cancer. By initially focusing on specific cancer types, such as the rhabdomyosarcoma family of myogenic soft tissue cancers, this research laboratory is investigating the molecular basis, biological consequences and clinical significance of chromosomal translocations, amplification events, point mutations and methylation changes in these cancers. The methodologies, reagents and concepts from these studies are then being applied to address these issues in other relevant cancer categories. Recent projects in the laboratory have been in the areas of:

1) Action of fusion oncoproteins (J. Pathol. - PMID: 28138962)

2) Mechanisms of tumor recurrence (Cancer Res. - PMID: 33589519)

3) Amplified genes as therapeutic targets (J. Clin. Invest. - PMID: 34166228)

4) DNA methylation-based classification (Int. J. Cancer - PMID: 30565669).

The selected candidate will work closely with a team of researchers in the Cancer Molecular Pathology section and will promote and support numerous interdisciplinary collaborations both within and outside the NIH. This is an exciting opportunity to join a growing and evolving cancer research effort across the basic, translational, and clinical research spectrum. The successful applicant will provide demonstrable leadership and mentoring in the planning, execution, interpretation and communication of research projects in the Cancer Molecular Pathology section. The selected candidate will also work closely with the section head to identify future research opportunities and develop a strategic plan to achieve these goals.

Qualifications and Job Details

Degree Required
Ph.D. or equivalent
Job Location
Bethesda
Appointment Type
Government Position (Salary commensurate with experience)
Work Schedule
Full-time
Citizenship
US Citizenship not required - (ie, permanent resident, visa)

Required and Preferred Skills

Required Skills

Interested candidates must have a doctoral degree and postdoctoral training in molecular biology, cell biology, biochemistry, genetics, or a related discipline. Strong oral and written communications skills are also essential in this position. Candidates will be evaluated on their educational background, scholarly work, leadership and mentoring potential, and communication skills.

About the NCI Center for Cancer Research

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Bethesda

Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.

How to Apply
Submit:
  • CV/Resume
  • 3 References
  • Summary of Research Experience
Additional Application Information

This position is subject to a background investigation.

Contact Information
Contact Name
Frederic G. Barr, MD PhD
E-mail Address
barrfg@mail.nih.gov
DHHS, NIH and NCI are equal opportunity employers. The NCI and CCR are deeply committed to diversity of thought, equity and inclusion and encourage applications from qualified women, underrepresented minorities and individuals with disabilities.