Postdoctoral Fellow - Biochemistry, enzymology

Date Posted
Position is with
Name of Hiring Official/Investigator

Job Description

This is a postdoctoral fellowship in the Protein Chemistry and Molecular Biology Section of the Molecular Targets Program. For more information, visit Dr. O'Keefe's profile.

Qualifications and Job Details

Degree Required
Ph.D. or equivalent
Job Location
Appointment Type
Training Position (Starting stipend: $65,100, bonuses may apply)
Work Schedule
Full-time (In-Person)
US Citizenship not required - (ie, permanent resident, visa)

Required and Preferred Skills

Required Skills

The selected candidate will be expected to conduct investigations into adapting laboratory cancer biology discoveries on molecular targets of interest for cancer into bioassays and high-throughput screens for the discovery of novel natural products. 

Preferred Skills

The candidate will also be involved in mechanism of action studies on natural products that display inhibitory activity against targets of interest.

About the NCI Center for Cancer Research

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.


Frederick is the second largest city in Maryland but retains a “small town” feel, surrounded by mountain views with a vibrant Main Street community. The city offers outstanding schools, a balanced and thriving economy and a highly educated workforce.

How to Apply
  • CV/Resume
  • Statement of Research Goals
  • 3 References
  • Cover Letter
  • Summary of Research Experience
  • Diversity Statement
Additional Application Information

The position is located at the NCI at Frederick Maryland campus. Candidates must have a Ph.D. in biochemistry, cell/molecular biology, biophysics, pharmacognosy or a related discipline from an accredited research institution within the last three years. The fellowship duration is for a maximum of 5 years based on performance and yearly evaluations. The fellowship is not restricted to U.S. citizens. The fellowship stipend starts at $65,100 per annum and is determined based on qualifications and years of relevant experience. Applicants should submit a cover letter, CV with bibliography, and three letters of reference to or directly to Dr. Barry R. O’Keefe at

Contact Information
Contact Name
Barry O'Keefe
E-mail Address
DHHS, NIH and NCI are equal opportunity employers. The NCI and CCR are deeply committed to diversity of thought, equity and inclusion and encourage applications from qualified women, underrepresented minorities and individuals with disabilities.