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Post-doctoral Fellow - Brain tumors, lipid metabolism, cancer biology

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Job Description

One postdoctoral position is available in the Larion laboratory at the Neuro-Oncology Branch, CCR, NCI. My laboratory is focused on understanding the metabolic changes in brain tumors. In particular, we are interested in revealing the lipid alterations of isocitrate dehydrogenase (IDH1)-mutated gliomas and in exploiting these deregulations for therapeutic applications. We employ a combination of methods such as molecular biology, animal models, as well as in vitro and in vivo metabolomics using Raman Imaging Microscopy, and Mass Spectrometry (MS).

The postdoctoral fellow will explore the link between lipid gene alterations in brain tumors and their biology. This position requires expertise in Western Blotting, mammalian cell culture and other common biomedical techniques used in cancer biology labs such as handling tissue samples, preparing tissue slides, staining, and extraction of proteins from brain tissue.

Qualifications and Job Details

Degree Required
Ph.D. or equivalent
M.D. or equivalent
Job Location
Bethesda
Appointment Type
Training Position (Stipend commensurate with experience)
Work Schedule
Full-time
Citizenship
US Citizenship not required - (ie, permanent resident, visa)

Required and Preferred Skills

Required Skills

Successful candidates should have: 1) experience in handling cell culture and tissue; 2) experience in manipulating human cell lines such as neurospheres, and different tissue, blood and urine samples; and 3) be highly independent in designing the experiments, analyzing the data and presenting the results.

About the NCI Center for Cancer Research

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Bethesda

Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.

How to Apply
Submit:
  • CV/Resume
  • Statement of Research Goals
  • Three References
  • Summary of Research Experience
Contact Information
Contact Name
Mioara Larion
E-mail Address
mioara.larion@nih.gov
DHHS, NIH and NCI are equal opportunity employers. The NCI and CCR are deeply committed to diversity of thought, equity and inclusion and encourage applications from qualified women, underrepresented minorities and individuals with disabilities.